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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 6 — Jun. 27, 2013

Three-dimensional light-scattering and deformation of individual biconcave human blood cells in optical tweezers

Lingyao Yu, Yunlong Sheng, and Arthur Chiou  »View Author Affiliations


Optics Express, Vol. 21, Issue 10, pp. 12174-12184 (2013)
http://dx.doi.org/10.1364/OE.21.012174


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Abstract

For studying the elastic properties of a biconcave red blood cell using the dual-trap optical tweezers without attaching microbeads to the cell, we implemented a three-dimensional finite element simulation of the light scattering and cell’s deformation using the coupled electromagnetic and continuum mechanics modules. We built the vector field of the trapping beams, the cell structure layout, the hyperelastic and viscoelastic cell materials, and we reinforced the constraints on the cell constant volume in the simulation. This computation model can be useful for studying the scattering and the other mechanical properties of the biological cells.

© 2013 OSA

OCIS Codes
(290.4210) Scattering : Multiple scattering
(350.4855) Other areas of optics : Optical tweezers or optical manipulation

ToC Category:
Optical Trapping and Manipulation

History
Original Manuscript: January 29, 2013
Revised Manuscript: March 31, 2013
Manuscript Accepted: April 3, 2013
Published: May 10, 2013

Virtual Issues
Vol. 8, Iss. 6 Virtual Journal for Biomedical Optics

Citation
Lingyao Yu, Yunlong Sheng, and Arthur Chiou, "Three-dimensional light-scattering and deformation of individual biconcave human blood cells in optical tweezers," Opt. Express 21, 12174-12184 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-21-10-12174


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