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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 8 — Sep. 4, 2013

Silicon-based optoelectronic integrated circuit for label-free bio/chemical sensor

Junfeng Song, Xianshu Luo, Jack Sheng Kee, Kyungsup Han, Chao Li, Mi Kyoung Park, Xiaoguang Tu, Huijuan Zhang, Qing Fang, Lianxi Jia, Yong-Jin Yoon, Tsung-Yang Liow, Mingbin Yu, and Guo-Qiang Lo  »View Author Affiliations

Optics Express, Vol. 21, Issue 15, pp. 17931-17940 (2013)

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Abstract: We demonstrate a silicon-based optoelectronic integrated circuit (OEIC) for label-free bio/chemical sensing application. Such on-chip OEIC sensor system consists of optical grating couplers for vertical light coupling into silicon waveguides, a thermal-tunable microring as a tunable filter, an exposed microring as an optical label-free sensor, and a Ge photodetector for a direct electrical readout. Different from the conventional wavelength-scanning method, we adopt low-cost broadband ASE light source, together with the on-chip tunable filter to generate sliced light source. The effective refractive index change of the sensing microring induced by the sensing target is traced by scanning the supplied electrical power applied onto the tracing microring, and the detected electrical signal is read out by the Ge photodetector. For bulk refractive index sensing, we demonstrate using such OEIC sensing system with a sensitivity of ~15 mW/RIU and a detection limit of 3.9 μ-RIU, while for surface sensing of biotin-streptavidin, we obtain a surface mass sensitivity of Sm = ~192 µW/ng·mm−2 and a surface detection limit of 0.3 pg/mm2. The presented OEIC sensing system is suitable for point-of-care applications.

© 2013 OSA

OCIS Codes
(040.5160) Detectors : Photodetectors
(130.0250) Integrated optics : Optoelectronics
(130.2790) Integrated optics : Guided waves
(130.3120) Integrated optics : Integrated optics devices
(220.4000) Optical design and fabrication : Microstructure fabrication
(230.3990) Optical devices : Micro-optical devices
(250.3140) Optoelectronics : Integrated optoelectronic circuits
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(280.4788) Remote sensing and sensors : Optical sensing and sensors

ToC Category:

Original Manuscript: March 12, 2013
Revised Manuscript: April 25, 2013
Manuscript Accepted: April 29, 2013
Published: July 19, 2013

Virtual Issues
Vol. 8, Iss. 8 Virtual Journal for Biomedical Optics

Junfeng Song, Xianshu Luo, Jack Sheng Kee, Kyungsup Han, Chao Li, Mi Kyoung Park, Xiaoguang Tu, Huijuan Zhang, Qing Fang, Lianxi Jia, Yong-Jin Yoon, Tsung-Yang Liow, Mingbin Yu, and Guo-Qiang Lo, "Silicon-based optoelectronic integrated circuit for label-free bio/chemical sensor," Opt. Express 21, 17931-17940 (2013)

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