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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 9 — Oct. 2, 2013

Second-harmonic generation in lithium niobate nanowires for local fluorescence excitation

Anton Sergeyev, Reinhard Geiss, Alexander S. Solntsev, Andrea Steinbrück, Frank Schrempel, Ernst-Bernhard Kley, Thomas Pertsch, and Rachel Grange  »View Author Affiliations

Optics Express, Vol. 21, Issue 16, pp. 19012-19021 (2013)

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We study the nonlinear optical properties of lithium niobate (LiNbO3) nanowires (NWs) fabricated by a top-down ion beam enhanced etching method. First, we demonstrate generation and propagation of the second-harmonic (SH) light in LiNbO3 NWs of typical rectangular cross-sections of 400 x 600 nm2 and length from 10 to 50 μm. Then, we show local fluorescent excitation of 4',6-diamidino-2-phenylindole (DAPI) dye with the propagated SH signal in standard concentrations as for biological applications. By measuring the detected average power of the propagated fundamental harmonic (FH) and the SH signal at the output of the NWs, we directly prove the dominating role of the SH signal over possible two-photon excitation processes with the FH in the DAPI dye. We estimate that 63 ± 6 pW of the propagated SH average power is required for detectable dye excitation. Finally, we model the waveguiding of the SH light to determine the smallest NW cross-section (around 40x60 nm2) which is potentially able to excite fluorescence with a FH intensity below the cell damage threshold.

© 2013 OSA

OCIS Codes
(190.2620) Nonlinear optics : Harmonic generation and mixing
(190.4180) Nonlinear optics : Multiphoton processes
(230.7370) Optical devices : Waveguides
(260.2510) Physical optics : Fluorescence

ToC Category:
Nonlinear Optics

Original Manuscript: May 21, 2013
Revised Manuscript: July 11, 2013
Manuscript Accepted: July 11, 2013
Published: August 2, 2013

Virtual Issues
Vol. 8, Iss. 9 Virtual Journal for Biomedical Optics

Anton Sergeyev, Reinhard Geiss, Alexander S. Solntsev, Andrea Steinbrück, Frank Schrempel, Ernst-Bernhard Kley, Thomas Pertsch, and Rachel Grange, "Second-harmonic generation in lithium niobate nanowires for local fluorescence excitation," Opt. Express 21, 19012-19021 (2013)

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