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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 10 — Nov. 8, 2013

Measurement depth enhancement in terahertz imaging of biological tissues

Seung Jae Oh, Sang-Hoon Kim, Kiyoung Jeong, Yeonji Park, Yong-Min Huh, Joo-Hiuk Son, and Jin-Suck Suh  »View Author Affiliations


Optics Express, Vol. 21, Issue 18, pp. 21299-21305 (2013)
http://dx.doi.org/10.1364/OE.21.021299


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Abstract

We demonstrate the use of a THz penetration-enhancing agent (THz-PEA) to enhance the terahertz (THz) wave penetration depth in tissues. The THz-PEA is a biocompatible material having absorption lower than that of water, and it is easily absorbed into tissues. When using glycerol as a THz-PEA, the peak value of the THz signal which was transmitted through the fresh tissue and reflected by a metal target, was almost doubled compared to that of tissue without glycerol. THz time-of-flight imaging (B-scan) was used to display the sequential glycerol delivery images. Enhancement of the penetration depth was confirmed after an artificial tumor was located below fresh skin. We thus concluded that the THz-PEA technique can potentially be employed to enhance the image contrast of the abnormal lesions below the skin.

© 2013 OSA

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6795) Medical optics and biotechnology : Terahertz imaging

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: June 20, 2013
Revised Manuscript: August 15, 2013
Manuscript Accepted: August 22, 2013
Published: September 4, 2013

Virtual Issues
Vol. 8, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Seung Jae Oh, Sang-Hoon Kim, Kiyoung Jeong, Yeonji Park, Yong-Min Huh, Joo-Hiuk Son, and Jin-Suck Suh, "Measurement depth enhancement in terahertz imaging of biological tissues," Opt. Express 21, 21299-21305 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-21-18-21299


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