Simultaneous multiple-depths en-face optical coherence tomography using multiple signal excitation of acousto-optic deflectors

doi:10.1364/OE.21.001925

Simultaneous multiple-depths en-face optical coherence tomography using multiple signal excitation of acousto-optic deflectors

Mantas Zurauskas, John Rogers, and Adrian Gh. Podoleanu »View Author Affiliations

Optics Express, Vol. 21, Issue 2, pp. 1925-1936 (2013)
http://dx.doi.org/10.1364/OE.21.001925

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Abstract
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References (15)
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Abstract

We present a novel low-coherence interferometer configuration, equipped with acousto-optic deflectors that can be used to simultaneously acquire up to eight time domain optical coherence tomography en-face images. The capabilities of the configuration are evaluated in terms of depth resolution, signal to noise ratio and crosstalk. Then the configuration is employed to demonstrate simultaneous en-face optical coherence tomography imaging at five different depths in a specimen of armadillidium vulgare.

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(110.6880) Imaging systems : Three-dimensional image acquisition
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(170.0110) Medical optics and biotechnology : Imaging systems
(170.1065) Medical optics and biotechnology : Acousto-optics

ToC Category:
Imaging Systems

History
Original Manuscript: November 8, 2012
Revised Manuscript: January 8, 2013
Manuscript Accepted: January 9, 2013
Published: January 17, 2013

Virtual Issues
Vol. 8, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Mantas Zurauskas, John Rogers, and Adrian Gh. Podoleanu, "Simultaneous multiple-depths en-face optical coherence tomography using multiple signal excitation of acousto-optic deflectors," Opt. Express 21, 1925-1936 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-21-2-1925

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References

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991). [CrossRef] [PubMed]
B. J. Vakoc, D. Fukumura, R. K. Jain, and B. E. Bouma, “Cancer imaging by optical coherence tomography: preclinical progress and clinical potential,” Nat. Rev. Cancer12(5), 363–368 (2012). [CrossRef] [PubMed]
A. Podoleanu, “Route to OCT from OFS at university of Kent,” Photonic Sens1(2), 166–186 (2011). [CrossRef]
A. G. Podoleanu, “Optical coherence tomography,” J. Microsc.247(3), 209–219 (2012). [CrossRef] [PubMed]
A. G. Podoleanu, G. M. Dobre, D. J. Webb, and D. A. Jackson, “Simultaneous en-face imaging of two layers in the human retina by low-coherence reflectometry,” Opt. Lett.22(13), 1039–1041 (1997). [CrossRef] [PubMed]
A. G. Podoleanu, J. A. Rogers, R. C. Cucu, D. A. Jackson, B. Wacogne, H. Porte, and T. Gharbi, “Simultaneous low coherence interferometry imaging at two depths using an integrated optic modulator,” Opt. Commun.191(1-2), 21–30 (2001). [CrossRef]
L. Neagu, A. Bradu, L. Ma, J. W. Bloor, and A. G. Podoleanu, “Multiple-depth en face optical coherence tomography using active recirculation loops,” Opt. Lett.35(13), 2296–2298 (2010). [CrossRef] [PubMed]
N. A. Riza and D. Psaltis, “Acousto-optic signal processors for transmission and reception of phased-array antenna signals,” Appl. Opt.30(23), 3294–3303 (1991). [CrossRef] [PubMed]
C. Hitzenberger, P. Trost, P. W. Lo, and Q. Zhou, “Three-dimensional imaging of the human retina by high-speed optical coherence tomography,” Opt. Express11(21), 2753–2761 (2003). [CrossRef] [PubMed]
N. A. Riza and Z. Yaqoob, “Submicrosecond speed optical coherence tomography system design and analysis by use of acousto-optics,” Appl. Opt.42(16), 3018–3026 (2003). [CrossRef] [PubMed]
N. A. Riza, “Acousto-optically switched optical delay lines,” Opt. Commun.145(1-6), 15–20 (1998). [CrossRef]
H. C. Ho, E. H. Young, and W. Seale, “Microwave frequency translation with multiple bragg cells,” P Soc Photo-Opt Ins 1703, 37-42 (1992).
A. P. Goutzoulis, D. R. Pape, and S. V. Kulakov, Design and fabrication of acousto-optic devices (Marcel Dekker, 1994).
A. Bradu, L. Neagu, and A. Podoleanu, “Extra long imaging range swept source optical coherence tomography using re-circulation loops,” Opt. Express18(24), 25361–25370 (2010). [CrossRef] [PubMed]
T. Klein, W. Wieser, C. M. Eigenwillig, B. R. Biedermann, and R. Huber, “Megahertz OCT for ultrawide-field retinal imaging with a 1050 nm Fourier domain mode-locked laser,” Opt. Express19(4), 3044–3062 (2011). [CrossRef] [PubMed]

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[1] D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science254(5035), 1178–1181 (1991). [CrossRef] [PubMed]

[2] B. J. Vakoc, D. Fukumura, R. K. Jain, and B. E. Bouma, “Cancer imaging by optical coherence tomography: preclinical progress and clinical potential,” Nat. Rev. Cancer12(5), 363–368 (2012). [CrossRef] [PubMed]

[3] A. Podoleanu, “Route to OCT from OFS at university of Kent,” Photonic Sens1(2), 166–186 (2011). [CrossRef]

[4] A. G. Podoleanu, “Optical coherence tomography,” J. Microsc.247(3), 209–219 (2012). [CrossRef] [PubMed]

[5] A. G. Podoleanu, G. M. Dobre, D. J. Webb, and D. A. Jackson, “Simultaneous en-face imaging of two layers in the human retina by low-coherence reflectometry,” Opt. Lett.22(13), 1039–1041 (1997). [CrossRef] [PubMed]

[6] A. G. Podoleanu, J. A. Rogers, R. C. Cucu, D. A. Jackson, B. Wacogne, H. Porte, and T. Gharbi, “Simultaneous low coherence interferometry imaging at two depths using an integrated optic modulator,” Opt. Commun.191(1-2), 21–30 (2001). [CrossRef]

[7] L. Neagu, A. Bradu, L. Ma, J. W. Bloor, and A. G. Podoleanu, “Multiple-depth en face optical coherence tomography using active recirculation loops,” Opt. Lett.35(13), 2296–2298 (2010). [CrossRef] [PubMed]

[8] N. A. Riza and D. Psaltis, “Acousto-optic signal processors for transmission and reception of phased-array antenna signals,” Appl. Opt.30(23), 3294–3303 (1991). [CrossRef] [PubMed]

[9] C. Hitzenberger, P. Trost, P. W. Lo, and Q. Zhou, “Three-dimensional imaging of the human retina by high-speed optical coherence tomography,” Opt. Express11(21), 2753–2761 (2003). [CrossRef] [PubMed]

[10] N. A. Riza and Z. Yaqoob, “Submicrosecond speed optical coherence tomography system design and analysis by use of acousto-optics,” Appl. Opt.42(16), 3018–3026 (2003). [CrossRef] [PubMed]

[11] N. A. Riza, “Acousto-optically switched optical delay lines,” Opt. Commun.145(1-6), 15–20 (1998). [CrossRef]

[12] H. C. Ho, E. H. Young, and W. Seale, “Microwave frequency translation with multiple bragg cells,” P Soc Photo-Opt Ins 1703, 37-42 (1992).

[13] A. P. Goutzoulis, D. R. Pape, and S. V. Kulakov, Design and fabrication of acousto-optic devices (Marcel Dekker, 1994).

[14] A. Bradu, L. Neagu, and A. Podoleanu, “Extra long imaging range swept source optical coherence tomography using re-circulation loops,” Opt. Express18(24), 25361–25370 (2010). [CrossRef] [PubMed]

[15] T. Klein, W. Wieser, C. M. Eigenwillig, B. R. Biedermann, and R. Huber, “Megahertz OCT for ultrawide-field retinal imaging with a 1050 nm Fourier domain mode-locked laser,” Opt. Express19(4), 3044–3062 (2011). [CrossRef] [PubMed]

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Simultaneous multiple-depths en-face optical coherence tomography using multiple signal excitation of acousto-optic deflectors