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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 3 — Apr. 4, 2013

Microfluidics integration of aperiodic plasmonic arrays for spatial-spectral optical detection

Sylvanus Y. Lee, Gary F. Walsh, and Luca Dal Negro  »View Author Affiliations


Optics Express, Vol. 21, Issue 4, pp. 4945-4957 (2013)
http://dx.doi.org/10.1364/OE.21.004945


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Abstract

We demonstrate successful integration of aperiodic arrays of metal nanoparticles with microfluidics technology for optical sensing using the spectral-colorimetric responses of nanostructured arrays to refractive index variations. Different aperiodic arrays of gold (Au) nanoparticles with varying interparticle separations and Fourier spectral properties are fabricated using Electron Beam Lithography (EBL) and integrated with polydimethylsiloxane (PDMS) microfluidics structures by soft-lithographic micro-imprint techniques. The spectral shifts of scattering spectra and the distinctive modifications of structural color patterns induced by refractive index variations were simultaneously measured inside microfluidic flow cells by dark-field spectroscopy and image correlation analysis in the visible spectral range. The integration of engineered aperiodic arrays of Au nanoparticles with microfluidics devices provides a novel sensing platform with multiplexed spatial-spectral responses for opto-fluidics applications and lab-on-a-chip optical biosensing.

© 2013 OSA

OCIS Codes
(290.3030) Scattering : Index measurements
(330.1710) Vision, color, and visual optics : Color, measurement
(280.4788) Remote sensing and sensors : Optical sensing and sensors

ToC Category:
Sensors

History
Original Manuscript: November 8, 2012
Revised Manuscript: February 12, 2013
Manuscript Accepted: February 14, 2013
Published: February 21, 2013

Virtual Issues
Vol. 8, Iss. 3 Virtual Journal for Biomedical Optics

Citation
Sylvanus Y. Lee, Gary F. Walsh, and Luca Dal Negro, "Microfluidics integration of aperiodic plasmonic arrays for spatial-spectral optical detection," Opt. Express 21, 4945-4957 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-21-4-4945


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