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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 4 — May. 22, 2013

Dual-coil magnetomotive optical coherence tomography for contrast enhancement in liquids

Jongsik Kim, Adeel Ahmad, and Stephen A. Boppart  »View Author Affiliations


Optics Express, Vol. 21, Issue 6, pp. 7139-7147 (2013)
http://dx.doi.org/10.1364/OE.21.007139


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Abstract

Magnetomotive optical coherence tomography (MM-OCT) is a functional extension of OCT which utilizes magnetically responsive materials that are modulated by an external magnetic field for contrast enhancement and for elastography to assess the structural and viscoelastic properties of the surrounding tissues. Traditionally, magnetomotive contrast relies on the interaction between the displacement of magnetic particles induced by an external magnetic field and the micro-environmental restoring (elastic) force acting on the particles. When the restoring force from a sample containing magnetic particles is weak or non-existent, the MM-OCT signal-to-noise ratio (SNR) can degrade significantly. We have developed a novel solenoid configuration to enable MM-OCT imaging in samples that do not have an elastic restoring force, such as liquids. This coil configuration may potentially enable real-time MM-OCT imaging.

© 2013 OSA

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.4090) Medical optics and biotechnology : Modulation techniques
(230.3810) Optical devices : Magneto-optic systems
(160.4236) Materials : Nanomaterials

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 23, 2013
Revised Manuscript: March 4, 2013
Manuscript Accepted: March 6, 2013
Published: March 14, 2013

Virtual Issues
Vol. 8, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Jongsik Kim, Adeel Ahmad, and Stephen A. Boppart, "Dual-coil magnetomotive optical coherence tomography for contrast enhancement in liquids," Opt. Express 21, 7139-7147 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-21-6-7139


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