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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 9, Iss. 3 — Mar. 6, 2014

Direct phase measurement in zonal wavefront reconstruction using multidither coherent optical adaptive technique

Rui Liu, Daniel E. Milkie, Aaron Kerlin, Bryan MacLennan, and Na Ji  »View Author Affiliations

Optics Express, Vol. 22, Issue 2, pp. 1619-1628 (2014)

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In traditional zonal wavefront sensing for adaptive optics, after local wavefront gradients are obtained, the entire wavefront can be calculated by assuming that the wavefront is a continuous surface. Such an approach will lead to sub-optimal performance in reconstructing wavefronts which are either discontinuous or undersampled by the zonal wavefront sensor. Here, we report a new method to reconstruct the wavefront by directly measuring local wavefront phases in parallel using multidither coherent optical adaptive technique. This method determines the relative phases of each pupil segment independently, and thus produces an accurate wavefront for even discontinuous wavefronts. We implemented this method in an adaptive optical two-photon fluorescence microscopy and demonstrated its superior performance in correcting large or discontinuous aberrations.

© 2014 Optical Society of America

OCIS Codes
(170.0180) Medical optics and biotechnology : Microscopy
(180.2520) Microscopy : Fluorescence microscopy
(220.1000) Optical design and fabrication : Aberration compensation
(220.1080) Optical design and fabrication : Active or adaptive optics

ToC Category:
Adaptive Optics

Original Manuscript: October 16, 2013
Revised Manuscript: December 30, 2013
Manuscript Accepted: January 3, 2014
Published: January 16, 2014

Virtual Issues
Vol. 9, Iss. 3 Virtual Journal for Biomedical Optics

Rui Liu, Daniel E. Milkie, Aaron Kerlin, Bryan MacLennan, and Na Ji, "Direct phase measurement in zonal wavefront reconstruction using multidither coherent optical adaptive technique," Opt. Express 22, 1619-1628 (2014)

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