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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 9, Iss. 4 — Apr. 1, 2014

Higher-order modulations of fs laser pulses for GHz frequency domain photon migration system

Huang-Yi Lin, Nanyu Cheng, Sheng-Hao Tseng, and Ming-Che Chan  »View Author Affiliations


Optics Express, Vol. 22, Issue 4, pp. 3950-3958 (2014)
http://dx.doi.org/10.1364/OE.22.003950


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Abstract

Except the fundamental modulation frequency, by higher-order-harmonic modulations of mode-locked laser pulses and a simple frequency demodulation circuit, a novel approach to GHz frequency-domain-photon-migration (FDPM) system was reported. With this novel approach, a wide-band modulation frequency comb is available without any external modulation devices and the only electronics to extract the optical attenuation and phase properties at a selected modulation frequency in FDPM systems are good mixers and lock-in devices. This approach greatly expands the frequency range that could be achieved by conventional FDPM systems and suggests that our system could extract much more information from biological tissues than the conventional FDPM systems. Moreover, this demonstration will be beneficial for discerning the minute change of tissue properties.

© 2014 Optical Society of America

OCIS Codes
(140.4050) Lasers and laser optics : Mode-locked lasers
(170.5280) Medical optics and biotechnology : Photon migration
(290.1990) Scattering : Diffusion

ToC Category:
Optoelectronics

History
Original Manuscript: November 4, 2013
Revised Manuscript: January 8, 2014
Manuscript Accepted: February 4, 2014
Published: February 12, 2014

Virtual Issues
Vol. 9, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Huang-Yi Lin, Nanyu Cheng, Sheng-Hao Tseng, and Ming-Che Chan, "Higher-order modulations of fs laser pulses for GHz frequency domain photon migration system," Opt. Express 22, 3950-3958 (2014)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=oe-22-4-3950


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