OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 9, Iss. 4 — Apr. 1, 2014

How to avoid a negative shift in reflection-type surface plasmon resonance biosensors with metallic nanostructures

Nak-Hyeon Kim, Tae Woo Kim, and Kyung Min Byun  »View Author Affiliations

Optics Express, Vol. 22, Issue 4, pp. 4723-4730 (2014)

View Full Text Article

Enhanced HTML    Acrobat PDF (2224 KB) Open Access

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



We experimentally demonstrate that introduction of a dielectric film can prevent the surface plasmon resonance (SPR) curve from being shifted to a smaller angle, called negative shift, which occurs unpredictably when metallic nanostructures deposited on a metal film are exposed to an adsorption of binding analytes. From parylene coating experiments, we find that the proposed reflection-type SPR system with a low refractive index MgF2 film and gold nanorods can provide an enhanced sensitivity by more than 6 times as well as a reliable positive shift. It is due to the fact that use of a dielectric film can contribute to the compensation of an anomalous dispersion relation and the prevention of a destructive interaction of propagating surface plasmons with multiple localized plasmon modes. Our approach is intended to show the feasibility and extend the applicability of the proposed SPR system to diverse biomolecular reactions.

© 2014 Optical Society of America

OCIS Codes
(240.6680) Optics at surfaces : Surface plasmons
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(310.6628) Thin films : Subwavelength structures, nanostructures

ToC Category:

Original Manuscript: October 14, 2013
Revised Manuscript: January 25, 2014
Manuscript Accepted: February 4, 2014
Published: February 21, 2014

Virtual Issues
Vol. 9, Iss. 4 Virtual Journal for Biomedical Optics

Nak-Hyeon Kim, Tae Woo Kim, and Kyung Min Byun, "How to avoid a negative shift in reflection-type surface plasmon resonance biosensors with metallic nanostructures," Opt. Express 22, 4723-4730 (2014)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. J. Homola, “Present and future of surface plasmon resonance biosensors,” Anal. Bioanal. Chem. 377(3), 528–539 (2003). [CrossRef] [PubMed]
  2. A. Shalabney, I. Abdulhalim, “Sensitivity-enhancement methods for surface plasmon sensors,” Laser Photon. Rev. 5(4), 571–606 (2011). [CrossRef]
  3. X. D. Hoa, A. G. Kirk, M. Tabrizian, “Towards integrated and sensitive surface plasmon resonance biosensors: a review of recent progress,” Biosens. Bioelectron. 23(2), 151–160 (2007). [CrossRef] [PubMed]
  4. L. He, M. D. Musick, S. R. Nicewarner, F. G. Salinas, S. J. Benkovic, M. J. Natan, C. D. Keating, “Colloidal Au-enhanced surface plasmon resonance for ultrasensitive detection of DNA hybridization,” J. Am. Chem. Soc. 122(38), 9071–9077 (2000). [CrossRef]
  5. L. A. Lyon, M. D. Musick, M. J. Natan, “Colloidal Au-enhanced surface plasmon resonance immunosensing,” Anal. Chem. 70(24), 5177–5183 (1998). [CrossRef] [PubMed]
  6. K. M. Byun, S. J. Kim, D. Kim, “Design study of highly sensitive nanowire-enhanced surface plasmon resonance biosensors using rigorous coupled wave analysis,” Opt. Express 13(10), 3737–3742 (2005). [CrossRef] [PubMed]
  7. K. M. Byun, S. J. Yoon, D. Kim, S. J. Kim, “Experimental study of sensitivity enhancement in surface plasmon resonance biosensors by use of periodic metallic nanowires,” Opt. Lett. 32(13), 1902–1904 (2007). [CrossRef] [PubMed]
  8. N.-H. Kim, W. K. Jung, K. M. Byun, “Correlation analysis between plasmon field distribution and sensitivity enhancement in reflection- and transmission-type localized surface plasmon resonance biosensors,” Appl. Opt. 50(25), 4982–4988 (2011). [CrossRef]
  9. S. M. Jang, D. Kim, S. H. Choi, K. M. Byun, S. J. Kim, “Enhancement of localized surface plasmon resonance detection by incorporating metal-dielectric double-layered subwavelength gratings,” Appl. Opt. 50(18), 2846–2854 (2011). [CrossRef] [PubMed]
  10. E. D. Palik, Handbook of Optical Constants of Solids (Academic, 1985).
  11. B. J. Jeon, M. H. Kim, J. C. Pyun, “Application of a functionalized parylene film as a linker layer of SPR biosensor,” Sens. Actuators B Chem. 154(2), 89–95 (2011). [CrossRef]
  12. T. Read, R. V. Olkhov, A. M. Shaw, “Measurement of the localised plasmon penetration depth for gold nanoparticles using a non-invasive bio-stacking method,” Phys. Chem. Chem. Phys. 15(16), 6122–6127 (2013). [CrossRef] [PubMed]
  13. E. T. Arakawa, M. W. Williams, R. N. Hamm, R. H. Ritchie, “Effect of damping on surface plasmon dispersion,” Phys. Rev. Lett. 31(18), 1127–1129 (1973). [CrossRef]
  14. R. W. Alexander, G. S. Kovener, R. J. Bell, “Dispersion curves for surface electromagnetic waves with damping,” Phys. Rev. Lett. 32(4), 154–157 (1974). [CrossRef]
  15. D. Kim, “Effect of resonant localized plasmon coupling on the sensitivity enhancement of nanowire-based surface plasmon resonance biosensors,” J. Opt. Soc. Am. A 23(9), 2307–2314 (2006). [CrossRef] [PubMed]
  16. Y. S. Jung, J. Wuenschell, H. K. Kim, P. Kaur, D. H. Waldeck, “Blue-shift of surface plasmon resonance in a metal nanoslit array structure,” Opt. Express 17(18), 16081–16091 (2009). [CrossRef] [PubMed]
  17. R. Micheletto, K. Hamamoto, T. Fujii, Y. Kawakami, “Tenfold improved sensitivity using high refractive-index substrates for surface plasmon sensing,” Appl. Phys. Lett. 93(17), 174104 (2008). [CrossRef]
  18. F. Bahrami, M. Maisonneuve, M. Meunier, J. S. Aitchison, M. Mojahedi, “An improved refractive index sensor based on genetic optimization of plasmon waveguide resonance,” Opt. Express 21(18), 20863–20872 (2013). [CrossRef] [PubMed]
  19. A. Shalabney, I. Abdulhalim, “Figure-of-merit enhancement of surface plasmon resonance sensors in the spectral interrogation,” Opt. Lett. 37(7), 1175–1177 (2012). [CrossRef] [PubMed]
  20. A. Lahav, M. Auslender, I. Abdulhalim, “Sensitivity enhancement of guided-wave surface-plasmon resonance sensors,” Opt. Lett. 33(21), 2539–2541 (2008). [CrossRef] [PubMed]
  21. H.-G. Flesch, O. Werzer, M. Weis, J. Jakabovič, J. Kováč, D. Haško, G. Jakopič, H. J. Wondergem, R. Resel, “A combined X-ray, ellipsometry and atomic force microscopy study on thin parylene-C films,” Phys. Status Solidi A 206(8), 1727–1730 (2009). [CrossRef]
  22. L. Qin, S. Zou, C. Xue, A. Atkinson, G. C. Schatz, C. A. Mirkin, “Designing, fabricating, and imaging Raman hot spots,” Proc. Natl. Acad. Sci. U.S.A. 103(36), 13300–13303 (2006). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited