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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 1, Iss. 7 — Jul. 17, 2006

Imaging cerebral blood flow through the intact rat skull with temporal laser speckle imaging

Pengcheng Li, Songlin Ni, Li Zhang, Shaoqun Zeng, and Qingming Luo  »View Author Affiliations


Optics Letters, Vol. 31, Issue 12, pp. 1824-1826 (2006)
http://dx.doi.org/10.1364/OL.31.001824


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Abstract

We discovered that laser speckle temporal contrast analysis (LSTCA) is able to access the two-dimensional (2D) cerebral blood flow velocity and vessel structure through the intact rat skull. It is demonstrated that LSTCA can significantly suppress the influence of the laser speckle from the stationary structure, such as the skull, and thus reveal the blood flow and morphology of blood vessels through the laser speckle images recorded from the intact rat skull.

© 2006 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.6480) Medical optics and biotechnology : Spectroscopy, speckle

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 19, 2006
Revised Manuscript: April 6, 2006
Manuscript Accepted: April 6, 2006

Virtual Issues
Vol. 1, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Pengcheng Li, Songlin Ni, Li Zhang, Shaoqun Zeng, and Qingming Luo, "Imaging cerebral blood flow through the intact rat skull with temporal laser speckle imaging," Opt. Lett. 31, 1824-1826 (2006)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-31-12-1824


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