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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 1, Iss. 11 — Nov. 13, 2006

Surface plasmon interferometric microscopy for three-dimensional imaging of dynamic processes

Jian Zhang, Qiwei Dai, and Guo Ping Wang  »View Author Affiliations


Optics Letters, Vol. 31, Issue 20, pp. 3004-3006 (2006)
http://dx.doi.org/10.1364/OL.31.003004


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Abstract

A method, which we named surface plasmon interferometric microscopy, for real-time displaying of the dynamic evolution of the refractive index (RI) of a sample in three-dimensions is demonstrated experimentally. The Fourier fringe analysis technique is employed to get the phase variations of the samples by demodulating the interference patterns captured by a CCD camera, and the 3D RI distribution can be obtained through numerical interpolation from the relation between the phase and the RI of the samples. Our method may provide an interesting way to monitor fast dynamics of physical, biological, and chemical processes in real time.

© 2006 Optical Society of America

OCIS Codes
(130.6010) Integrated optics : Sensors
(170.6920) Medical optics and biotechnology : Time-resolved imaging
(180.3170) Microscopy : Interference microscopy
(240.6680) Optics at surfaces : Surface plasmons

ToC Category:
Microscopy

History
Original Manuscript: June 20, 2006
Revised Manuscript: August 5, 2006
Manuscript Accepted: August 5, 2006
Published: September 25, 2006

Virtual Issues
Vol. 1, Iss. 11 Virtual Journal for Biomedical Optics

Citation
Jian Zhang, Qiwei Dai, and Guo Ping Wang, "Surface plasmon interferometric microscopy for three-dimensional imaging of dynamic processes," Opt. Lett. 31, 3004-3006 (2006)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-31-20-3004

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