OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 1 — Jan. 19, 2007

Pulsed near-infrared laser diode excitation system for biomedical photoacoustic imaging

Thomas J. Allen and Paul C. Beard  »View Author Affiliations

Optics Letters, Vol. 31, Issue 23, pp. 3462-3464 (2006)

View Full Text Article

Enhanced HTML    Acrobat PDF (194 KB)

Browse Journals / Lookup Meetings

Browse by Journal and Year


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools



A pulsed laser diode system operating at 905 nm has been developed for the generation of photoacoustic signals in tissue. It was evaluated by measuring the photoacoustic waveforms generated in a blood vessel phantom comprising three dye-filled ( μ a = 1 mm 1 ) tubes of diameters 120 580 μ m immersed to a maximum depth of 9 mm in a turbid liquid ( μ s = 1 mm 1 ) . The system was then combined with a cylindrical scanning system to obtain two-dimensional images of a tissue phantom. The signal-to-noise ratio of the detected signals in both cases and the image contrast in the latter suggest that such a system could provide a compact and inexpensive alternative to current excitation sources for superficial imaging applilcations.

© 2006 Optical Society of America

OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(300.6430) Spectroscopy : Spectroscopy, photothermal

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: July 31, 2006
Manuscript Accepted: August 24, 2006
Published: November 9, 2006

Virtual Issues
Vol. 2, Iss. 1 Virtual Journal for Biomedical Optics

Thomas J. Allen and Paul C. Beard, "Pulsed near-infrared laser diode excitation system for biomedical photoacoustic imaging," Opt. Lett. 31, 3462-3464 (2006)

Sort:  Author  |  Year  |  Journal  |  Reset  


  1. M. Xu and L. V. Wang, Rev. Sci. Instrum. 77, 041101 (2006). [CrossRef]
  2. J. Laufer, C. E. Elwell, D. T. Delpy, and P. C. Beard, Phys. Med. Biol. 50, 4409 (2005). [CrossRef] [PubMed]
  3. Z. Zhao and R. Myllyla, Meas. Sci. Technol. 12, 2172 (2001). [CrossRef]
  4. R. G. M. Kolkman, W. Steenbergen, and T. G. van Leeuwen, Lasers Med. Sci. 21, 134 (2006). [CrossRef] [PubMed]
  5. T. J. Allen, B. T. Cox, P. C. Beard, in Proc. SPIE 5696, 233 (2005). [CrossRef]
  6. M. Xu and L. V. Wang, IEEE Trans. Biomed. Eng. 50, 1086 (2003). [CrossRef] [PubMed]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.


Fig. 1 Fig. 2 Fig. 3
Fig. 4 Fig. 5

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited