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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editor: Gregory W. Faris
  • Vol. 1, Iss. 4 — Apr. 12, 2006

Imaging and sizing of diamond nanoparticles

Yannick Colpin, Amanda Swan, Andrei V. Zvyagin, and Taras Plakhotnik  »View Author Affiliations

Optics Letters, Vol. 31, Issue 5, pp. 625-627 (2006)

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Typical disturbances of biological environment such as background scatter and refractive index variations have little effect on the size-dependent scattering property of highly refractive nanocrystals, which are potentially attractive optical labels. We report on what is to our knowledge the first investigation of these scattering optical labels, and their sizing, in particular, by imaging at subvideo frame rates and analyzing samples of diamond nanocrystals deposited on a glass substrate in air and in a matrix of weakly scattering polymer. The brightness of a diffraction-limited spot appears to serve as a reliable measure of the particle size in the Rayleigh scattering limit.

© 2006 Optical Society of America

OCIS Codes
(110.2960) Imaging systems : Image analysis
(120.5820) Instrumentation, measurement, and metrology : Scattering measurements
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(290.5870) Scattering : Scattering, Rayleigh

ToC Category:

Original Manuscript: September 9, 2005
Revised Manuscript: October 24, 2005
Manuscript Accepted: October 26, 2005

Virtual Issues
Vol. 1, Iss. 4 Virtual Journal for Biomedical Optics

Yannick Colpin, Amanda Swan, Andrei V. Zvyagin, and Taras Plakhotnik, "Imaging and sizing of diamond nanoparticles," Opt. Lett. 31, 625-627 (2006)

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