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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 1, Iss. 4 — Apr. 12, 2006

Hemoglobin contrast in magnetomotive optical Doppler tomography

Jeehyun Kim, Junghwan Oh, Thomas E. Milner, and J. Stuart Nelson  »View Author Affiliations


Optics Letters, Vol. 31, Issue 6, pp. 778-780 (2006)
http://dx.doi.org/10.1364/OL.31.000778


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Abstract

We introduce a novel contrast mechanism for imaging blood flow by use of magnetomotive optical Doppler tomography (MM-ODT), which combines an externally applied temporally oscillating high-strength magnetic field with ODT to detect erythrocytes moving according to the field gradient. Hemoglobin contrast was demonstrated in a capillary tube filled with moving blood by imaging the Doppler frequency shift, which was observed independently of blood flow rate and direction. Results suggest that MM-ODT may be a promising technique with which to image blood flow.

© 2006 Optical Society of America

OCIS Codes
(160.3820) Materials : Magneto-optical materials
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(290.5850) Scattering : Scattering, particles

ToC Category:
Medical Optics and Biotechnology

Virtual Issues
Vol. 1, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Jeehyun Kim, Junghwan Oh, Thomas E. Milner, and J. Stuart Nelson, "Hemoglobin contrast in magnetomotive optical Doppler tomography," Opt. Lett. 31, 778-780 (2006)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-31-6-778

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