We report on the development of a miniature, flexible, fiber-optic scanning endoscope for two-photon fluorescence imaging. The endoscope uses a tubular piezoelectric actuator for achieving two-dimensional beam scanning and a double-clad fiber for delivery of the excitation light and collection of two-photon fluorescence. Real-time imaging of fluorescent beads and cancer cells has been performed.
© 2006 Optical Society of America
Medical Optics and Biotechnology
Original Manuscript: October 6, 2005
Manuscript Accepted: November 19, 2005
Vol. 1, Iss. 5 Virtual Journal for Biomedical Optics
Mon Thiri Myaing, Daniel J. MacDonald, and Xingde Li, "Fiber-optic scanning two-photon fluorescence endoscope," Opt. Lett. 31, 1076-1078 (2006)