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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 7 — Jul. 16, 2007

6450 nm wavelength tissue ablation using a nanosecond laser based on difference frequency mixing and stimulated Raman scattering

G. S. Edwards, R. D. Pearlstein, M. L. Copeland, M. S. Hutson, K. Latone, A. Spiro, and G. Pasmanik  »View Author Affiliations


Optics Letters, Vol. 32, Issue 11, pp. 1426-1428 (2007)
http://dx.doi.org/10.1364/OL.32.001426


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Abstract

A four-stage laser system was developed, emitting at a wavelength of 6450 nm with a 3 5 ns pulse duration, 2 mJ pulse energy, and 1 2 Hz pulse repetition rate. The laser system successfully ablated rat brain tissue, where both the collateral damage and the ablation rate compare favorably with that previously observed with a Mark-III Free-Electron Laser.

© 2007 Optical Society of America

OCIS Codes
(140.3070) Lasers and laser optics : Infrared and far-infrared lasers
(170.1020) Medical optics and biotechnology : Ablation of tissue
(170.3890) Medical optics and biotechnology : Medical optics instrumentation

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: January 26, 2007
Revised Manuscript: March 2, 2007
Manuscript Accepted: March 9, 2007
Published: April 30, 2007

Virtual Issues
Vol. 2, Iss. 7 Virtual Journal for Biomedical Optics

Citation
G. S. Edwards, R. D. Pearlstein, M. L. Copeland, M. S. Hutson, K. Latone, A. Spiro, and G. Pasmanik, "6450 nm wavelength tissue ablation using a nanosecond laser based on difference frequency mixing and stimulated Raman scattering," Opt. Lett. 32, 1426-1428 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-32-11-1426


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References

  1. G. S. Edwards, R. H. Austin, F. E. Carroll, M. L. Copeland, M. E. Couprie, W. E. Gabella, R. F. Haglund, B. A. Hooper, M. S. Hutson, E. D. Jansen, K. M. Joos, D. P. Kiehart, I. Lindau, J. Miao, H. S. Pratisto, J. H. Shen, Y. Tokutake, L. van der Meer, and A. Xie, Rev. Sci. Instrum. 74, 3207 (2003), and references therein. [CrossRef]
  2. M. A. Mackanos, B. Ivanov, A. N. Soldatov, I. Kostadinov, M. H. Mendenhall, D. W. Piston, R. F. Haglund, and E. D. Jansen, Proc. SPIE 5319, 201 (2004). [CrossRef]
  3. M. A. Mackanos, J. A. Kozub, and E. D. Jansen, Phys. Med. Biol. 50, 1871 (2005). [CrossRef] [PubMed]
  4. M. S. Hutson, S. A. Hauger, and G. Edwards, Phys. Rev. E 65, 061906 (2002). [CrossRef]
  5. S. Kuznetsov, G. Pasmanik, A. Shilov, and L. Tiour, Opt. Lett. 29, 848 (2004). [CrossRef] [PubMed]

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