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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 7 — Jul. 16, 2007

Estimation of the scattering coefficients of turbid media using angle-resolved optical frequency-domain imaging

A. E. Desjardins, B. J. Vakoc, A. Bilenca, G. J. Tearney, and B. E. Bouma  »View Author Affiliations


Optics Letters, Vol. 32, Issue 11, pp. 1560-1562 (2007)
http://dx.doi.org/10.1364/OL.32.001560


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Abstract

Noninvasive measurements of the scattering coefficients of optically turbid media using angle-resolved optical frequency-domain imaging (OFDI) are demonstrated. It is shown that, by incoherently averaging OFDI reflectance signals acquired at different backscattering angles, speckle noise is reduced, allowing scattering coefficients to be extracted from a single A-line with much higher accuracy than with measurements from conventional OFDI and optical coherence tomography systems. Modeling speckle as a random phasor sum, the relationship between the measurement accuracy and the number of compounded angles is derived. The sensitivity analysis is validated with measurements from a tissue phantom.

© 2007 Optical Society of America

OCIS Codes
(120.5820) Instrumentation, measurement, and metrology : Scattering measurements
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Instrumentation, Measurement, and Metrology

History
Original Manuscript: January 31, 2007
Revised Manuscript: March 5, 2007
Manuscript Accepted: March 9, 2007
Published: May 16, 2007

Virtual Issues
Vol. 2, Iss. 7 Virtual Journal for Biomedical Optics

Citation
A. E. Desjardins, B. J. Vakoc, A. Bilenca, G. J. Tearney, and B. E. Bouma, "Estimation of the scattering coefficients of turbid media using angle-resolved optical frequency-domain imaging," Opt. Lett. 32, 1560-1562 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-32-11-1560


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