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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 8 — Aug. 10, 2007

High-resolution line-scanning optical coherence microscopy

Yu Chen, Shu-Wei Huang, Aaron D. Aguirre, and James G. Fujimoto  »View Author Affiliations


Optics Letters, Vol. 32, Issue 14, pp. 1971-1973 (2007)
http://dx.doi.org/10.1364/OL.32.001971


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Abstract

An optical coherence microscopy system based on line illumination and detection is demonstrated. The system uses a Linnik-type interferometer illuminated by a broadband Ti:sapphire laser and detected by a high-speed, line-scan CCD camera. This approach is less sensitive to incoherent scattering and sample motion than full-field imaging. Spatial resolutions of 2 μ m × 3 μ m ( transverse × axial ) are achieved. The sensitivity of the system is 93 dB with averaging over 30 line scans. En face real time, cellular-level imaging of biological tissues is demonstrated at 2   frames s .

© 2007 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(180.0180) Microscopy : Microscopy

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: February 26, 2007
Manuscript Accepted: April 2, 2007
Published: July 3, 2007

Virtual Issues
Vol. 2, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Yu Chen, Shu-Wei Huang, Aaron D. Aguirre, and James G. Fujimoto, "High-resolution line-scanning optical coherence microscopy," Opt. Lett. 32, 1971-1973 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-32-14-1971

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