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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 8 — Aug. 10, 2007

Optimizing immersion media refractive index improves optical trapping by compensating spherical aberrations

S. Nader S. Reihani and Lene B. Oddershede  »View Author Affiliations

Optics Letters, Vol. 32, Issue 14, pp. 1998-2000 (2007)

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The efficiency of an optical trap is limited by its axial strength. Light focused by oil-immersion objectives provides stronger traps but suffers from spherical aberrations, thus restricting the axial stability and working distance. By changing the refractive index of the immersion media we compensate spherical aberrations and measure axial trapping strengths at least twice as large as previously reported. Moreover, the spherical aberrations can be compensated at any desired depth. The improved trapping efficiency implies significantly less heating of the particles, thus diminishing previously published concerns about using gold nanoparticles as handles for optical manipulation.

© 2007 Optical Society of America

OCIS Codes
(140.7010) Lasers and laser optics : Laser trapping
(170.1790) Medical optics and biotechnology : Confocal microscopy
(220.1000) Optical design and fabrication : Aberration compensation

ToC Category:
Lasers and Laser Optics

Original Manuscript: January 9, 2007
Revised Manuscript: May 8, 2007
Manuscript Accepted: May 9, 2007
Published: July 3, 2007

Virtual Issues
Vol. 2, Iss. 8 Virtual Journal for Biomedical Optics

S. Nader S. Reihani and Lene B. Oddershede, "Optimizing immersion media refractive index improves optical trapping by compensating spherical aberrations," Opt. Lett. 32, 1998-2000 (2007)

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