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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 9 — Sep. 26, 2007

Unified Mie and fractal scattering by biological cells and subcellular structures

Tao T. Wu, Jianan Y. Qu, and Min Xu  »View Author Affiliations


Optics Letters, Vol. 32, Issue 16, pp. 2324-2326 (2007)
http://dx.doi.org/10.1364/OL.32.002324


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Abstract

Angle-resolved light scattering spectroscopy of biological cells is investigated in the visible wavelength range. A unified Mie and fractal model is shown to provide an accurate global agreement with light scattering spectra from 1.1° to 165° scattering angles. It is found that light scattering in forward directions ( < 8 ° ) is dominated by Mie scattering by the bare cell and nucleus, whereas light scattering at large angles ( > 20 ° ) is determined by fractal scattering by subcellular structures. The findings are consistent with the results of experimental investigation of the contributions of different cellular components to light scattering by cells.

© 2007 Optical Society of America

OCIS Codes
(120.5820) Instrumentation, measurement, and metrology : Scattering measurements
(170.1530) Medical optics and biotechnology : Cell analysis
(290.0290) Scattering : Scattering
(290.4020) Scattering : Mie theory

ToC Category:
Scattering

History
Original Manuscript: April 17, 2007
Revised Manuscript: June 8, 2007
Manuscript Accepted: June 20, 2007
Published: August 2, 2007

Virtual Issues
Vol. 2, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Tao T. Wu, Jianan Y. Qu, and Min Xu, "Unified Mie and fractal scattering by biological cells and subcellular structures," Opt. Lett. 32, 2324-2326 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-32-16-2324


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References

  1. L. T. Perelman, V. Backman, M. Wallace, G. Zonios, R. Manoharan, A. Nusrat, S. Shields, M. Seiler, C. Lima, T. Hamano, I. Itzkan, J. Van Dam, J. M. Crawford, and M. S. Feld, Phys. Rev. Lett. 80, 627 (1998). [CrossRef]
  2. K. Sokolov, R. Drezek, K. Gossage, and R. Richards-Kortum, Opt. Express 5, 302 (1999). [CrossRef] [PubMed]
  3. A. Wax, C. Yang, V. Backman, K. Badizadegan, C. W. Boone, R. R. Dasari, and M. S. Feld, Biophys. J. 82, 2256 (2002). [CrossRef] [PubMed]
  4. J. R. Mourant, T. M. Johnson, S. Carpenter, A. Guerra, T. Aida, and J. P. Freyer, J. Biomed. Opt. 7, 378 (2002). [CrossRef] [PubMed]
  5. Z. Chen, A. Taflove, and V. Backman, Opt. Lett. 28, 765 (2003). [CrossRef] [PubMed]
  6. X. Li, A. Taflove, and V. Backman, IEEE J. Sel. Top. Quantum Electron. 11, 759 (2005). [CrossRef]
  7. R. S. Brock, X. H. Hu, D. A. Weidner, J. R. Mourant, and J. Q. Lu, J. Quant. Spectrosc. Radiat. Transf. 102, 25 (2006). [CrossRef]
  8. M. Xu, T. T. Wu, and J. Y. Qu, Proc. SPIE 6446, 64460Y (2007). [CrossRef]
  9. M. Moscoso, J. B. Keller, and G. Papanicolaou, J. Opt. Soc. Am. A 18, 948 (2001). [CrossRef]
  10. M. Xu and R. R. Alfano, Opt. Lett. 30, 3051 (2005). [CrossRef] [PubMed]
  11. M. C. Anderson, J. A. Jordan, A. R. Morse, and F. Sharp, A Text and Atlas of Integrated Colposcopy: for Colposcopists, Histopathologists and Cytologists (Chapman & Hall Medical, 1992).
  12. T. T. Wu and J. Y. Qu, Appl. Opt. 46, 4834 (2007). [CrossRef] [PubMed]
  13. W. J. Wiscombe, Appl. Opt. 19, 1505 (1980). [CrossRef] [PubMed]
  14. A. Dunn, http://www.nmr.mgh.harvard.edu/~adunn/papers/dissertation/node73.html.
  15. R. Lambert, J. F. Rey, and R. Sankaranarayanan, Endoscopy 35, 437 (2003). [CrossRef] [PubMed]

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