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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 3 — Mar. 7, 2007

Needle-based refractive index measurement using low-coherence interferometry

Adam M. Zysk, Steven G. Adie, Julian J. Armstrong, Matthew S. Leigh, Alexandre Paduch, David D. Sampson, Freddy T. Nguyen, and Stephen A. Boppart  »View Author Affiliations


Optics Letters, Vol. 32, Issue 4, pp. 385-387 (2007)
http://dx.doi.org/10.1364/OL.32.000385


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Abstract

We present a novel needle-based device for the measurement of refractive index and scattering using low-coherence interferometry. Coupled to the sample arm of an optical coherence tomography system, the device detects the scattering response of, and optical path length through, a sample residing in a fixed-width channel. We report use of the device to make near-infrared measurements of tissues and materials with known optical properties. The device could be used to exploit the refractive index variations of tissue for medical and biological diagnostics accessible by needle insertion.

© 2007 Optical Society of America

OCIS Codes
(110.2350) Imaging systems : Fiber optics imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(290.3030) Scattering : Index measurements

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: August 4, 2006
Revised Manuscript: October 20, 2006
Manuscript Accepted: November 3, 2006
Published: January 26, 2007

Virtual Issues
Vol. 2, Iss. 3 Virtual Journal for Biomedical Optics

Citation
Adam M. Zysk, Steven G. Adie, Julian J. Armstrong, Matthew S. Leigh, Alexandre Paduch, David D. Sampson, Freddy T. Nguyen, and Stephen A. Boppart, "Needle-based refractive index measurement using low-coherence interferometry," Opt. Lett. 32, 385-387 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-32-4-385

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