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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 2, Iss. 5 — May. 17, 2007

Phase-sensitive detection of dipole radiation in a fiber-based high numerical aperture optical system

A. N. Vamivakas, S. B. Ippolito, A. K. Swan, M. S. Ünlü, M. Dogan, E. R. Behringer, and B. B. Goldberg  »View Author Affiliations


Optics Letters, Vol. 32, Issue 8, pp. 970-972 (2007)
http://dx.doi.org/10.1364/OL.32.000970


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Abstract

We theoretically study the problem of detecting dipole radiation in a fiber-based confocal microscope of high numerical aperture. By using a single-mode fiber, in contrast to a hard-stop pinhole aperture, the detector becomes sensitive to the phase of the field amplitude. We find that the maximum in collection efficiency of the dipole radiation does not coincide with the optimum resolution for the light-gathering instrument. The derived expressions are important for analyzing fiber-based confocal microscope performance in fluorescence and spectroscopic studies of single molecules and/or quantum dots.

© 2007 Optical Society of America

OCIS Codes
(180.1790) Microscopy : Confocal microscopy
(260.1960) Physical optics : Diffraction theory
(260.2110) Physical optics : Electromagnetic optics
(300.6280) Spectroscopy : Spectroscopy, fluorescence and luminescence

ToC Category:
Physical Optics

History
Original Manuscript: September 20, 2006
Revised Manuscript: December 29, 2006
Manuscript Accepted: January 4, 2007
Published: March 19, 2007

Virtual Issues
Vol. 2, Iss. 5 Virtual Journal for Biomedical Optics

Citation
A. N. Vamivakas, S. B. Ippolito, A. K. Swan, M. S. Ünlü, M. Dogan, E. R. Behringer, and B. B. Goldberg, "Phase-sensitive detection of dipole radiation in a fiber-based high numerical aperture optical system," Opt. Lett. 32, 970-972 (2007)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-32-8-970


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References

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