In contrast to fluorescence enhancement of fluorophores embedded in a photonic crystal structure as previously reported [ Appl. Phys. Lett. 75, 3605 (1999) ], in this Letter we demonstrate a unique approach to forming an open microcavity using a one-dimensional photonic crystal in a total-internal-reflection geometry. This configuration opens up the possibility for enhancing fluorescence imaging and biosensing. Time-resolved fluorescence detection of fluorophores immobilized on the open cavity has been carried out. Over 20-fold fluorescence enhancement was observed.
© 2008 Optical Society of America
Original Manuscript: April 23, 2008
Manuscript Accepted: June 5, 2008
Published: July 29, 2008
Vol. 3, Iss. 9 Virtual Journal for Biomedical Optics
Jing Yong Ye and Mitsuru Ishikawa, "Enhancing fluorescence detection with a photonic crystal structure in a total-internal-reflection configuration," Opt. Lett. 33, 1729-1731 (2008)