Enhancing fluorescence detection with a photonic crystal structure in a total-internal-reflection configuration
Optics Letters, Vol. 33, Issue 15, pp. 1729-1731 (2008)
http://dx.doi.org/10.1364/OL.33.001729
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Abstract
In contrast to fluorescence enhancement of fluorophores embedded in a photonic crystal structure as previously reported [ Appl. Phys. Lett. 75, 3605 (1999) ], in this Letter we demonstrate a unique approach to forming an open microcavity using a one-dimensional photonic crystal in a total-internal-reflection geometry. This configuration opens up the possibility for enhancing fluorescence imaging and biosensing. Time-resolved fluorescence detection of fluorophores immobilized on the open cavity has been carried out. Over 20-fold fluorescence enhancement was observed.
© 2008 Optical Society of America
OCIS Codes
(120.2230) Instrumentation, measurement, and metrology : Fabry-Perot
(230.5298) Optical devices : Photonic crystals
ToC Category:
Optical Devices
History
Original Manuscript: April 23, 2008
Manuscript Accepted: June 5, 2008
Published: July 29, 2008
Virtual Issues
Vol. 3, Iss. 9 Virtual Journal for Biomedical Optics
Citation
Jing Yong Ye and Mitsuru Ishikawa, "Enhancing fluorescence detection with a photonic crystal structure in a total-internal-reflection configuration," Opt. Lett. 33, 1729-1731 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-33-15-1729
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