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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 3, Iss. 10 — Sep. 22, 2008

Diffuse reflectance spectroscopy with a self-calibrating fiber optic probe

Bing Yu, Henry Fu, Torre Bydlon, Janelle E. Bender, and Nirmala Ramanujam  »View Author Affiliations


Optics Letters, Vol. 33, Issue 16, pp. 1783-1785 (2008)
http://dx.doi.org/10.1364/OL.33.001783


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Abstract

Calibration of the diffuse reflectance spectrum for instrument response and time-dependent fluctuation as well as interdevice variations is complicated, time consuming, and potentially inaccurate. We describe a novel fiber optic probe with a real-time self-calibration capability that can be used for tissue optical spectroscopy. The probe was tested in a number of liquid phantoms over a relevant range of tissue optical properties. Absorption and scattering coefficients are extracted with an average absolute error and standard deviation of 6.9 % ± 7.2 % and 3.5 % ± 1.5 % , respectively.

© 2008 Optical Society of America

OCIS Codes
(060.2370) Fiber optics and optical communications : Fiber optics sensors
(170.6510) Medical optics and biotechnology : Spectroscopy, tissue diagnostics

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 12, 2008
Revised Manuscript: June 20, 2008
Manuscript Accepted: June 30, 2008
Published: August 4, 2008

Virtual Issues
Vol. 3, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Bing Yu, Henry Fu, Torre Bydlon, Janelle E. Bender, and Nirmala Ramanujam, "Diffuse reflectance spectroscopy with a self-calibrating fiber optic probe," Opt. Lett. 33, 1783-1785 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-33-16-1783

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