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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 3, Iss. 12 — Dec. 1, 2008

Polarization-sensitive optoacoustic tomography of optically diffuse tissues

Daniel Razansky, Claudio Vinegoni, and Vasilis Ntziachristos  »View Author Affiliations


Optics Letters, Vol. 33, Issue 20, pp. 2308-2310 (2008)
http://dx.doi.org/10.1364/OL.33.002308


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Abstract

Polarization is indicative of material anisotropy, a property that reveals structural orientation information of molecules inside the material. Herein we investigate whether polarization can be detected optoacoustically in scattering and absorbing tissues. Using a laboratory prototype of polarization-sensitive optoacoustic tomography, we demonstrate high-resolution reconstructions of dichroism contrast deep in optically diffusive tissue-mimicking phantoms. The technique is expected to enable highly accurate imaging of polarization contrast in tissues, far beyond the current capabilities of pure optical polarization-imaging approaches.

© 2008 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(170.7050) Medical optics and biotechnology : Turbid media
(290.5855) Scattering : Scattering, polarization

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: June 10, 2008
Revised Manuscript: August 12, 2008
Manuscript Accepted: August 25, 2008
Published: October 9, 2008

Virtual Issues
Vol. 3, Iss. 12 Virtual Journal for Biomedical Optics

Citation
Daniel Razansky, Claudio Vinegoni, and Vasilis Ntziachristos, "Polarization-sensitive optoacoustic tomography of optically diffuse tissues," Opt. Lett. 33, 2308-2310 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-33-20-2308

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