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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 3, Iss. 4 — Apr. 23, 2008

Polarization-interferometric surface-plasmon-resonance imaging system

Ju-Yi Lee, Teng-Ko Chou, and Hsueh-Ching Shih  »View Author Affiliations


Optics Letters, Vol. 33, Issue 5, pp. 434-436 (2008)
http://dx.doi.org/10.1364/OL.33.000434


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Abstract

A two-dimensional phase-detection system for a surface-plasmon-resonance sensor is presented. The sensor utilizes polarization interferometry to detect phase differences between the s and p polarizations. We successfully detected a spatial phase-difference variation, resulting from the biomolecular interactions, of less than 1 × 1 mm 2 . The phase stability demonstrated in the experimental results was approximately 0.09°, and the corresponding change in the refractive index detection limit was approximately 4.3 × 10 6 . The common-optical-path configuration of the proposed method allowed us to reduce disturbances from ambient conditions. Furthermore, this method is capable of real-time array detection.

© 2008 Optical Society of America

OCIS Codes
(120.3180) Instrumentation, measurement, and metrology : Interferometry
(120.5050) Instrumentation, measurement, and metrology : Phase measurement
(240.6680) Optics at surfaces : Surface plasmons

ToC Category:
Instrumentation, Measurement, and Metrology

History
Original Manuscript: August 29, 2007
Revised Manuscript: January 25, 2008
Manuscript Accepted: January 25, 2008
Published: February 20, 2008

Virtual Issues
Vol. 3, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Ju-Yi Lee, Teng-Ko Chou, and Hsueh-Ching Shih, "Polarization-interferometric surface-plasmon-resonance imaging system," Opt. Lett. 33, 434-436 (2008)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-33-5-434

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