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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 4, Iss. 8 — Jul. 30, 2009

Molecular identification by generating coherence between molecular normal modes using stimulated Raman scattering

Daniel L. Marks, Joseph B. Geddes, III, and Stephen A. Boppart  »View Author Affiliations


Optics Letters, Vol. 34, Issue 12, pp. 1756-1758 (2009)
http://dx.doi.org/10.1364/OL.34.001756


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Abstract

We propose a method of driving the vibrations of normal modes of a target molecule into coherence using stimulated Raman scattering. In concert many vibrations can produce a larger anti-Stokes signal than a single vibration. The same illumination does not drive other molecules to have coherent vibrations so that these molecules produce a weaker signal. We investigate how target and confounder molecules can be distinguished by pulses that drive many vibrations coherently, which has applications in coherent Raman microspectroscopy.

© 2009 Optical Society of America

OCIS Codes
(170.5660) Medical optics and biotechnology : Raman spectroscopy
(190.5650) Nonlinear optics : Raman effect
(300.6450) Spectroscopy : Spectroscopy, Raman

ToC Category:
Spectroscopy

History
Original Manuscript: October 31, 2008
Revised Manuscript: January 16, 2009
Manuscript Accepted: February 10, 2009
Published: June 2, 2009

Virtual Issues
Vol. 4, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Daniel L. Marks, Joseph B. Geddes III, and Stephen A. Boppart, "Molecular identification by generating coherence between molecular normal modes using stimulated Raman scattering," Opt. Lett. 34, 1756-1758 (2009)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-34-12-1756

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