Label-free photoacoustic ophthalmic angiography
Optics Letters, Vol. 35, Issue 1, pp. 1-3 (2010)
http://dx.doi.org/10.1364/OL.35.000001
Enhanced HTML 
Acrobat PDF (331 KB)
Abstract
We present label-free functional photoacoustic imaging of the ocular microvasculature in living animals. The anterior segment of an adult mouse was imaged with a laser exposure level well within the American National Standards Institute safety standards. Individual red blood cells traveling along the iris capillaries were clearly resolved, and the hemoglobin oxygen saturation in the iris microvasculature was imaged spectrally. We believe that photoacoustic imaging has the potential to advance the diagnosis and treatment of ocular diseases in humans.
© 2009 Optical Society of America
OCIS Codes
(140.3360) Lasers and laser optics : Laser safety and eye protection
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(330.7327) Vision, color, and visual optics : Visual optics, ophthalmic instrumentation
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: September 10, 2009
Revised Manuscript: November 15, 2009
Manuscript Accepted: November 16, 2009
Published: December 17, 2009
Virtual Issues
Vol. 5, Iss. 2 Virtual Journal for Biomedical Optics
Citation
Song Hu, Bin Rao, Konstantin Maslov, and Lihong V. Wang, "Label-free photoacoustic ophthalmic angiography," Opt. Lett. 35, 1-3 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-35-1-1
You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
Multimedia
| Multimedia Files | Recommended Software |
| » Media 1: MOV (2800 KB) | QuickTime |
You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.
Contact your librarian or system administrator
or
Log in to access OSA Member Subscription
Related Journal Articles 
- Three-dimensional photoacoustic imaging of blood vessels in tissue (OL)
- Three-dimensional laser-induced photoacoustic tomography of mouse brain with the skin and skull intact (OL)
- Optoacoustic diffraction tomography: analysis of algorithms (JOSAA)
- Noninvasive photoacoustic angiography of animal brains in vivo with near-infrared light and an optical contrast agent (OL)
- Imaging of tumor angiogenesis in rat brains in vivo by photoacoustic tomography (AO)
Related Conference Papers
- Scanning thermoacoustic tomograhy in biological tissue
- Tissue Scaffolding Diagnostics with Femtosecond Laser Radiation
- Biomedical OpticsTissue Scaffolding Diagnostics with Femtosecond Laser Radiation
- Tissue Scaffolding Diagnostics with Femtosecond Laser Radiation
- In vivo Functional Imaging Using Photoacoustic Microscopy
OSA is a member of 