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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 2 — Jan. 21, 2010

Rapid volumetric angiography of cortical microvasculature with optical coherence tomography

Vivek J. Srinivasan, James Y. Jiang, Mohammed A. Yaseen, Harsha Radhakrishnan, Weicheng Wu, Scott Barry, Alex E. Cable, and David A. Boas  »View Author Affiliations


Optics Letters, Vol. 35, Issue 1, pp. 43-45 (2010)
http://dx.doi.org/10.1364/OL.35.000043


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Abstract

We describe methods and algorithms for rapid volumetric imaging of cortical vasculature with optical coherence tomography (OCT). By optimizing system design, scanning protocols, and algorithms for visualization of capillary flow, comprehensive imaging of the surface pial vasculature and capillary bed is performed in approximately 12 ‚ÄČ s . By imaging during hypercapnia and comparing with simultaneous CCD imaging, the sources of contrast of OCT angiography are investigated.

© 2009 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5380) Medical optics and biotechnology : Physiology

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: October 9, 2009
Revised Manuscript: November 23, 2009
Manuscript Accepted: November 25, 2009
Published: December 24, 2009

Virtual Issues
Vol. 5, Iss. 2 Virtual Journal for Biomedical Optics

Citation
Vivek J. Srinivasan, James Y. Jiang, Mohammed A. Yaseen, Harsha Radhakrishnan, Weicheng Wu, Scott Barry, Alex E. Cable, and David A. Boas, "Rapid volumetric angiography of cortical microvasculature with optical coherence tomography," Opt. Lett. 35, 43-45 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-35-1-43


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