Preclinical photoacoustic imaging endoscope based on acousto-optic coaxial system using ring transducer array
Optics Letters, Vol. 35, Issue 13, pp. 2266-2268 (2010)
http://dx.doi.org/10.1364/OL.35.002266
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Abstract
We developed and fabricated a preclinical photoacoustic imaging endoscope (PAIE) with an acousto-optic coaxial structure for cavity imaging that integrates a Plexiglas tube, an optical fiber, a ring transducer array, a taper reflector, and an ultrasonic coupling medium. A photoacoustic image for a section of pig colorectal tissue embedded in a transparent gelatin phantom was reconstructed. Furthermore, human colorectal cancer and normal colorectal tissue were imaged ex vivo with a contrast ratio of ~2.3. Experimental results demonstrate that the PAIE has potential for detecting colorectal cancer in clinical use.
© 2010 Optical Society of America
OCIS Codes
(110.5120) Imaging systems : Photoacoustic imaging
(170.1420) Medical optics and biotechnology : Biology
(170.2150) Medical optics and biotechnology : Endoscopic imaging
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: April 1, 2010
Revised Manuscript: May 28, 2010
Manuscript Accepted: June 8, 2010
Published: June 29, 2010
Virtual Issues
Vol. 5, Iss. 11 Virtual Journal for Biomedical Optics
Citation
Yi Yuan, Sihua Yang, and Da Xing, "Preclinical photoacoustic imaging endoscope based on acousto-optic coaxial system using ring transducer array," Opt. Lett. 35, 2266-2268 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-35-13-2266
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