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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editor: Gregory W. Faris
  • Vol. 5, Iss. 11 — Aug. 25, 2010

Crosstalk rejection in parallel optical coherence tomography using spatially incoherent illumination with partially coherent sources

Al-Hafeez Dhalla, Justin V. Migacz, and Joseph A. Izatt  »View Author Affiliations


Optics Letters, Vol. 35, Issue 13, pp. 2305-2307 (2010)
http://dx.doi.org/10.1364/OL.35.002305


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Abstract

The continuing improvement of high-speed area-scan cameras has made possible the construction of parallel optical coherence tomography (OCT) systems that are competitive with the fastest demonstrated swept-source OCT systems. Unfortunately, when imaging through turbid media using a partially coherent source, parallel OCT suffers resolution loss from coherent multiple scattering, a phenomenon known as crosstalk. We demonstrate the use of a full-field OCT system employing multimode fiber in the illumination arm to reduce the spatial coherence of a partially coherent source. By reducing the spatial coherence area below the system’s lateral resolution, we create a spatial coherence gate that rejects these multiply scattered photons. We quantify the image quality and resolution improvement of this method by comparing images of a USAF test chart acquired beneath turbid phantoms using both coherent and incoherent illumination and computing the resulting modulation transfer functions. We demonstrate the feasibility of this method for imaging biological specimens by imaging a Drosophila melanogaster sample.

© 2010 Optical Society of America

OCIS Codes
(110.4500) Imaging systems : Optical coherence tomography
(110.4980) Imaging systems : Partial coherence in imaging
(290.4210) Scattering : Multiple scattering
(290.7050) Scattering : Turbid media
(110.0113) Imaging systems : Imaging through turbid media
(110.2945) Imaging systems : Illumination design

ToC Category:
Imaging Systems

History
Original Manuscript: April 8, 2010
Revised Manuscript: June 10, 2010
Manuscript Accepted: June 10, 2010
Published: June 30, 2010

Virtual Issues
Vol. 5, Iss. 11 Virtual Journal for Biomedical Optics

Citation
Al-Hafeez Dhalla, Justin V. Migacz, and Joseph A. Izatt, "Crosstalk rejection in parallel optical coherence tomography using spatially incoherent illumination with partially coherent sources," Opt. Lett. 35, 2305-2307 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-35-13-2305


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