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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 5, Iss. 14 — Nov. 16, 2010

Ultrabroadband background-free coherent anti-Stokes Raman scattering microscopy based on a compact Er:fiber laser system

Romedi Selm, Martin Winterhalder, Andreas Zumbusch, Günther Krauss, Tobias Hanke, Alexander Sell, and Alfred Leitenstorfer  »View Author Affiliations


Optics Letters, Vol. 35, Issue 19, pp. 3282-3284 (2010)
http://dx.doi.org/10.1364/OL.35.003282


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Abstract

We demonstrate a scheme for efficient coherent anti-Stokes Raman scattering (CARS) microscopy free of nonresonant background. Our method is based on a compact Er:fiber laser source. Impulsive excitation of molecular resonances is achieved by an 11 fs pulse at 1210 nm . Broadband excitation gives access to molecular resonances from 0 cm 1 up to 4000 cm 1 . Time-delayed narrowband probing at 775 nm enables sensitive and high-speed spectral detection of the CARS signal free of nonresonant background with a resolution of 10 cm 1 .

© 2010 Optical Society of America

OCIS Codes
(140.3500) Lasers and laser optics : Lasers, erbium
(140.3510) Lasers and laser optics : Lasers, fiber
(170.5810) Medical optics and biotechnology : Scanning microscopy
(190.7110) Nonlinear optics : Ultrafast nonlinear optics
(300.6230) Spectroscopy : Spectroscopy, coherent anti-Stokes Raman scattering

ToC Category:
Microscopy

History
Original Manuscript: May 18, 2010
Revised Manuscript: August 3, 2010
Manuscript Accepted: August 13, 2010
Published: September 28, 2010

Virtual Issues
Vol. 5, Iss. 14 Virtual Journal for Biomedical Optics

Citation
Romedi Selm, Martin Winterhalder, Andreas Zumbusch, Günther Krauss, Tobias Hanke, Alexander Sell, and Alfred Leitenstorfer, "Ultrabroadband background-free coherent anti-Stokes Raman scattering microscopy based on a compact Er:fiber laser system," Opt. Lett. 35, 3282-3284 (2010)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-35-19-3282

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