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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 5, Iss. 14 — Nov. 16, 2010

Surface-enhanced Raman scattering substrates of high-density and high-homogeneity hot spots by magneto–metal nanoprobe assembling

Lu Zhang, Wen-Fei Dong, Zhi-Yong Tang, Jun-Feng Song, Hong Xia, and Hong-Bo Sun  »View Author Affiliations

Optics Letters, Vol. 35, Issue 19, pp. 3297-3299 (2010)

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Binary naoparticles composed of a superparamagnetic Fe 3 O 4 core and an Au nanoshell were prepared via a high-temperature hydrolysis reaction followed by seed-mediated growth. The nanoprobes render simultaneous dual functions of both fast magnetic response and local surface plasmon resonance. Using these nanoprobes, analyte molecules can be easily biologically captured, magnetically concentrated, and analyzed by surface-enhanced Raman scattering (SERS). Particularly, the complex particles were assembled under magnetic force direction into a SERS substrate. It was found to possess both a high enhancement factor ( 10 6 ) and high homogeneity of “hot spot” distribution (fluctuation less than 20% for a 1 μm 2 area) with 4-aminothiophenol as the analyte.

© 2010 Optical Society of America

OCIS Codes
(160.3820) Materials : Magneto-optical materials
(170.5660) Medical optics and biotechnology : Raman spectroscopy
(280.1545) Remote sensing and sensors : Chemical analysis
(240.6695) Optics at surfaces : Surface-enhanced Raman scattering

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Original Manuscript: June 1, 2010
Revised Manuscript: September 11, 2010
Manuscript Accepted: September 13, 2010
Published: September 30, 2010

Virtual Issues
Vol. 5, Iss. 14 Virtual Journal for Biomedical Optics

Lu Zhang, Wen-Fei Dong, Zhi-Yong Tang, Jun-Feng Song, Hong Xia, and Hong-Bo Sun, "Surface-enhanced Raman scattering substrates of high-density and high-homogeneity hot spots by magneto–metal nanoprobe assembling," Opt. Lett. 35, 3297-3299 (2010)

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