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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 7 — Jul. 27, 2011

Measurement of particle concentration in flow by statistical analyses of optical coherence tomography signals

Yi Wang and Ruikang K. Wang  »View Author Affiliations

Optics Letters, Vol. 36, Issue 11, pp. 2143-2145 (2011)

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We present a statistic method to measure the concentration of particles in flow by the use of optical coherence tomography (OCT). This method is based on the fact that the fluctuating numbers of particles contained within a small OCT detection volume caused by Brownian motion are governed by Poissonian distribution. Particle concentration is evaluated from the statistical analyzes of the OCT intensity signals that are backscattered by the moving particles. The method is experimentally verified with flow phantoms of polymer microspheres. Experimental results are in good agreement with the theoretical ones for low concentrations while relatively large discrepancies emerge for high concentrations.

© 2011 Optical Society of America

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(170.3880) Medical optics and biotechnology : Medical and biological imaging

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: April 4, 2011
Revised Manuscript: May 6, 2011
Manuscript Accepted: May 12, 2011
Published: June 1, 2011

Virtual Issues
Vol. 6, Iss. 7 Virtual Journal for Biomedical Optics

Yi Wang and Ruikang K. Wang, "Measurement of particle concentration in flow by statistical analyses of optical coherence tomography signals," Opt. Lett. 36, 2143-2145 (2011)

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