This study utilizes experimentally validated Monte Carlo simulations to identify a mathematical formulation of the reflectance intensity collected by a single fiber probe expressed in terms of the reduced scattering coefficient ( ${\mu }_s^{\prime }$ ), fiber diameter $d_{\text{fiber}}$ , and a property of the first two moments of the scattering phase function (γ). This model is then utilized to accurately obtain wavelength-dependent estimates of ${\mu }_s^{\prime }(\lambda )$ and $\gamma (\lambda )$ from multiple single fiber spectral measurements of a turbid medium obtained with different diameters. This method returns accurate descriptions (mean residual $<3\%$ ) of both ${\mu }_s^{\prime }$ and γ across the biologically relevant range.

© 2011 Optical Society of America

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