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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 9 — Oct. 3, 2011

Individual particle handling in a microfluidic system based on parallel laser trapping

Philippe Hamel, Bastien Rachet, Michael Werner, Mathieu Grossenbacher, Horst Vogel, Martin Forrer, Peter Ryser, and René P. Salathé  »View Author Affiliations


Optics Letters, Vol. 36, Issue 16, pp. 3182-3184 (2011)
http://dx.doi.org/10.1364/OL.36.003182


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Abstract

We present an optical trapping system combining individually addressable multiple laser traps with fluorescence spectroscopy. An in-line set of 64 near-IR laser diodes is used to create a line of individually addressable traps inside a microfluidic chip. This system is completed by an excitation/detection line for spectrally resolved fluorescence imaging of trapped particles. Highly parallel trapping in a constant flow (up to a few millimeters per second), fast particle handling rates (up to a few particles per second), and the possibility of recording fluorescence spectra of trapped objects lead to a performing bioanalytical platform, e.g., for highly parallel analysis and sorting.

© 2011 Optical Society of America

OCIS Codes
(170.3890) Medical optics and biotechnology : Medical optics instrumentation
(230.0230) Optical devices : Optical devices
(300.6280) Spectroscopy : Spectroscopy, fluorescence and luminescence
(350.4855) Other areas of optics : Optical tweezers or optical manipulation

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: April 18, 2011
Revised Manuscript: July 12, 2011
Manuscript Accepted: July 18, 2011
Published: August 11, 2011

Virtual Issues
Vol. 6, Iss. 9 Virtual Journal for Biomedical Optics

Citation
Philippe Hamel, Bastien Rachet, Michael Werner, Mathieu Grossenbacher, Horst Vogel, Martin Forrer, Peter Ryser, and René P. Salathé, "Individual particle handling in a microfluidic system based on parallel laser trapping," Opt. Lett. 36, 3182-3184 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-36-16-3182


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