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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 1 — Jan. 4, 2012

Multispectral optoacoustic tomography by means of normalized spectral ratio

Thomas Jetzfellner, Amir Rosenthal, Andreas Buehler, Karl-Hans Englmeier, Daniel Razansky, and Vasilis Ntziachristos  »View Author Affiliations


Optics Letters, Vol. 36, Issue 21, pp. 4176-4178 (2011)
http://dx.doi.org/10.1364/OL.36.004176


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Abstract

Quantification of biomarkers using multispectral optoacoustic tomography can be challenging due to photon fluence variations with depth and spatially heterogeneous tissue optical properties. Herein we introduce a spectral ratio approach that accounts for photon fluence variations. The performance and imaging improvement achieved with the proposed method is showcased both numerically and experimentally in phantoms and mice.

© 2011 Optical Society of America

OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(170.6960) Medical optics and biotechnology : Tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: June 29, 2011
Manuscript Accepted: September 9, 2011
Published: October 20, 2011

Virtual Issues
Vol. 7, Iss. 1 Virtual Journal for Biomedical Optics

Citation
Thomas Jetzfellner, Amir Rosenthal, Andreas Buehler, Karl-Hans Englmeier, Daniel Razansky, and Vasilis Ntziachristos, "Multispectral optoacoustic tomography by means of normalized spectral ratio," Opt. Lett. 36, 4176-4178 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-36-21-4176


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References

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