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Multispectral optoacoustic tomography by means of normalized spectral ratio |
Optics Letters, Vol. 36, Issue 21, pp. 4176-4178 (2011)
http://dx.doi.org/10.1364/OL.36.004176
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Abstract
Quantification of biomarkers using multispectral optoacoustic tomography can be challenging due to photon fluence variations with depth and spatially heterogeneous tissue optical properties. Herein we introduce a spectral ratio approach that accounts for photon fluence variations. The performance and imaging improvement achieved with the proposed method is showcased both numerically and experimentally in phantoms and mice.
© 2011 Optical Society of America
OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.5120) Medical optics and biotechnology : Photoacoustic imaging
(170.6960) Medical optics and biotechnology : Tomography
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: June 29, 2011
Manuscript Accepted: September 9, 2011
Published: October 20, 2011
Virtual Issues
Vol. 7, Iss. 1 Virtual Journal for Biomedical Optics
Citation
Thomas Jetzfellner, Amir Rosenthal, Andreas Buehler, Karl-Hans Englmeier, Daniel Razansky, and Vasilis Ntziachristos, "Multispectral optoacoustic tomography by means of normalized spectral ratio," Opt. Lett. 36, 4176-4178 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-36-21-4176
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