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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 6, Iss. 4 — May. 4, 2011

Investigation of surface plasmon biosensing using gold nanoparticles enhanced ellipsometry

Rakesh Singh Moirangthem, Yia-Chung Chang, and Pei-Kuen Wei  »View Author Affiliations


Optics Letters, Vol. 36, Issue 5, pp. 775-777 (2011)
http://dx.doi.org/10.1364/OL.36.000775


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Abstract

We present a label-free, nondestructive and high sensitivity biosensor by using the phase information of a gold nanoparticles enhanced ellipsometry signal. The refractive index (RI) resolution from ellipsometric phase information is of the order of 1.6 × 10 6 RI units. Furthermore, spectroscopic and dynamic measurements show substantial change in the phase signal when biomolecules are coated on gold nanoparticles. The detection limit of our proposed technique is up to 18 pM concentration of the target biomolecules.

© 2011 Optical Society of America

OCIS Codes
(260.2130) Physical optics : Ellipsometry and polarimetry
(280.1415) Remote sensing and sensors : Biological sensing and sensors
(280.4788) Remote sensing and sensors : Optical sensing and sensors
(250.5403) Optoelectronics : Plasmonics

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: October 26, 2010
Revised Manuscript: January 19, 2011
Manuscript Accepted: February 2, 2011
Published: March 1, 2011

Virtual Issues
Vol. 6, Iss. 4 Virtual Journal for Biomedical Optics

Citation
Rakesh Singh Moirangthem, Yia-Chung Chang, and Pei-Kuen Wei, "Investigation of surface plasmon biosensing using gold nanoparticles enhanced ellipsometry," Opt. Lett. 36, 775-777 (2011)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-36-5-775

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