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Noncontact all-optical measurement of corneal elasticity |
Optics Letters, Vol. 37, Issue 10, pp. 1625-1627 (2012)
http://dx.doi.org/10.1364/OL.37.001625
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Abstract
We report on a noninvasive and noncontact all-optical method to measure the elasticity of the cornea. We use a pulsed laser to excite surface acoustic waves (SAW) that propagate on the corneal surface, then use a phase-sensitive optical coherence tomography system to remotely record the SAWs from which the corneal elasticity is estimated. In addition, the system is able to provide real-time tomographic images of the cornea being examined, an important consideration for clinical studies. While precisely maintaining a range of intraocular pressures (IOP), a series of measurements is performed on ex vivo intact primate eyes. The measurement results not only demonstrate the feasibility of the proposed system to remotely measure the corneal elasticity, but also suggest a strong correlation between the corneal stiffness and the true IOP.
© 2012 Optical Society of America
OCIS Codes
(170.0170) Medical optics and biotechnology : Medical optics and biotechnology
(170.4460) Medical optics and biotechnology : Ophthalmic optics and devices
(240.6690) Optics at surfaces : Surface waves
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: February 22, 2012
Revised Manuscript: March 28, 2012
Manuscript Accepted: March 28, 2012
Published: May 7, 2012
Virtual Issues
Vol. 7, Iss. 7 Virtual Journal for Biomedical Optics
Citation
Chunhui Li, G. Guan, Z. Huang, M. Johnstone, and R. K. Wang, "Noncontact all-optical measurement of corneal elasticity," Opt. Lett. 37, 1625-1627 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-37-10-1625
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