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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 7 — Jun. 25, 2012

Fiber four-wave mixing source for coherent anti-Stokes Raman scattering microscopy

Simon Lefrancois, Dan Fu, Gary R. Holtom, Lingjie Kong, William J. Wadsworth, Patrick Schneider, Robert Herda, Armin Zach, X. Sunney Xie, and Frank W. Wise  »View Author Affiliations


Optics Letters, Vol. 37, Issue 10, pp. 1652-1654 (2012)
http://dx.doi.org/10.1364/OL.37.001652


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Abstract

We present a fiber-format picosecond light source for coherent anti-Stokes Raman scattering microscopy. Pulses from a Yb-doped fiber amplifier are frequency converted by four-wave mixing (FWM) in normal-dispersion photonic crystal fiber to produce a synchronized two-color picosecond pulse train. We show that seeding the FWM process overcomes the deleterious effects of group-velocity mismatch and allows efficient conversion into narrow frequency bands. The source generates more than 160 mW of nearly transform-limited pulses tunable from 775 to 815 nm. High-quality coherent Raman images of animal tissues and cells acquired with this source are presented.

© 2012 Optical Society of America

OCIS Codes
(190.4970) Nonlinear optics : Parametric oscillators and amplifiers
(320.7140) Ultrafast optics : Ultrafast processes in fibers
(180.5655) Microscopy : Raman microscopy

ToC Category:
Microscopy

History
Original Manuscript: January 11, 2012
Revised Manuscript: February 27, 2012
Manuscript Accepted: March 5, 2012
Published: May 9, 2012

Virtual Issues
Vol. 7, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Simon Lefrancois, Dan Fu, Gary R. Holtom, Lingjie Kong, William J. Wadsworth, Patrick Schneider, Robert Herda, Armin Zach, X. Sunney Xie, and Frank W. Wise, "Fiber four-wave mixing source for coherent anti-Stokes Raman scattering microscopy," Opt. Lett. 37, 1652-1654 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-37-10-1652

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