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Needle optical coherence elastography for tissue boundary detection |
Optics Letters, Vol. 37, Issue 12, pp. 2310-2312 (2012)
http://dx.doi.org/10.1364/OL.37.002310
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Abstract
We incorporate, for the first time, optical coherence elastography (OCE) into a needle probe and demonstrate its ability to measure the microscopic deformation of soft tissues located well beyond the depth limit of reports to date. Needle OCE utilizes the force imparted by the needle tip as the loading mechanism and measures tissue deformation ahead of the needle during insertion. Measurements were performed in tissue-mimicking phantoms and ex vivo porcine trachea. Results demonstrate differentiation of tissues based on mechanical properties and highlight the potential of needle OCE for in vivo tissue boundary detection.
© 2012 Optical Society of America
OCIS Codes
(170.2150) Medical optics and biotechnology : Endoscopic imaging
(170.4500) Medical optics and biotechnology : Optical coherence tomography
(170.6935) Medical optics and biotechnology : Tissue characterization
ToC Category:
Medical Optics and Biotechnology
History
Original Manuscript: March 9, 2012
Revised Manuscript: April 5, 2012
Manuscript Accepted: April 11, 2012
Published: June 8, 2012
Virtual Issues
Vol. 7, Iss. 8 Virtual Journal for Biomedical Optics
Citation
Kelsey M. Kennedy, Brendan F. Kennedy, Robert A. McLaughlin, and David D. Sampson, "Needle optical coherence elastography for tissue boundary detection," Opt. Lett. 37, 2310-2312 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-37-12-2310
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