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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 9 — Aug. 28, 2012

Speckle reduction of endovascular optical coherence tomography using a generalized divergence measure

Kyle H. Y. Cheng, Edmund Y. Lam, Beau A. Standish, and Victor X. D. Yang  »View Author Affiliations

Optics Letters, Vol. 37, Issue 14, pp. 2871-2873 (2012)

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Endovascular optical coherence tomography (EV-OCT) is an emerging intravascular imaging technique for observing blood vessel walls. Fluctuating speckle noise, especially during rapid pull-back, can severely degrade the visibility of morphological structures. Moreover, the speckle pattern varies in different parts of the image due to beam divergence and is further complicated by interpolation through the coordinate transformation necessary for displaying the rotary scanning images, challenging the use of frequency domain analysis. In this study, a computationally efficient method using a generalized divergence regularization procedure is presented to suppress speckle noise in EV-OCT images. Results show substantial smoothing of the grainy appearance and enhanced visualization of deeper structures as demonstrated in porcine carotid arteries.

© 2012 Optical Society of America

OCIS Codes
(100.2000) Image processing : Digital image processing
(100.2980) Image processing : Image enhancement
(100.3190) Image processing : Inverse problems
(170.1610) Medical optics and biotechnology : Clinical applications
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: March 28, 2012
Revised Manuscript: May 25, 2012
Manuscript Accepted: May 29, 2012
Published: July 11, 2012

Virtual Issues
Vol. 7, Iss. 9 Virtual Journal for Biomedical Optics

Kyle H. Y. Cheng, Edmund Y. Lam, Beau A. Standish, and Victor X. D. Yang, "Speckle reduction of endovascular optical coherence tomography using a generalized divergence measure," Opt. Lett. 37, 2871-2873 (2012)

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