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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 7, Iss. 10 — Oct. 5, 2012

Structured interference optical coherence tomography

Ji Yi, Qing Wei, Hao F. Zhang, and Vadim Backman  »View Author Affiliations


Optics Letters, Vol. 37, Issue 15, pp. 3048-3050 (2012)
http://dx.doi.org/10.1364/OL.37.003048


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Abstract

We developed a structured interference optical coherence tomography (SIOCT) to enhance the lateral resolution beyond the diffraction limit. A sinusoidal pattern is created on the interferometric beam with the reference intensity temporally modulated. In the Fourier domain, the high spatial frequencies are shifted into the detectable range, which enhances the lateral resolution beyond the diffraction limit by a factor of 2. The lateral resolution of SIOCT was characterized in our study as 5.5μm, surpassing the diffraction limit 9.6μm as in conventional Fourier-domain optical coherence tomography. SIOCT was demonstrated on phantoms and ex vivo adipose tissues.

© 2012 Optical Society of America

OCIS Codes
(100.6640) Image processing : Superresolution
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 16, 2012
Revised Manuscript: May 24, 2012
Manuscript Accepted: June 6, 2012
Published: July 16, 2012

Virtual Issues
Vol. 7, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Ji Yi, Qing Wei, Hao F. Zhang, and Vadim Backman, "Structured interference optical coherence tomography," Opt. Lett. 37, 3048-3050 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-37-15-3048


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