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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 1 — Feb. 4, 2013

Deep and optically resolved imaging through scattering media by space-reversed propagation

W. Glastre, O. Jacquin, O. Hugon, H. Guillet de Chatellus, and E. Lacot  »View Author Affiliations


Optics Letters, Vol. 37, Issue 23, pp. 4823-4825 (2012)
http://dx.doi.org/10.1364/OL.37.004823


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Abstract

We propose a novel technique of microscopy to overcome the effects of both scattering and limitation of the accessible depth due to the objective working distance. By combining laser optical feedback imaging with acoustic photon tagging and synthetic aperture refocusing we demonstrate an ultimate shot noise sensitivity at low power (required to preserve the tissues) and a high resolution beyond the microscope working distance. More precisely, with a laser power of 10 mW, we obtain images with a micrometric resolution over approximately eight transport mean free paths, corresponding to 1.3 times the microscope working distance. Various applications such as biomedical diagnosis and research and development of new drugs and therapies can benefit from our imaging setup.

© 2012 Optical Society of America

OCIS Codes
(170.0110) Medical optics and biotechnology : Imaging systems
(180.1790) Microscopy : Confocal microscopy
(290.7050) Scattering : Turbid media
(170.1065) Medical optics and biotechnology : Acousto-optics
(090.1995) Holography : Digital holography

ToC Category:
Scattering

History
Original Manuscript: September 7, 2012
Revised Manuscript: October 18, 2012
Manuscript Accepted: October 22, 2012
Published: November 16, 2012

Virtual Issues
Vol. 8, Iss. 1 Virtual Journal for Biomedical Optics

Citation
W. Glastre, O. Jacquin, O. Hugon, H. Guillet de Chatellus, and E. Lacot, "Deep and optically resolved imaging through scattering media by space-reversed propagation," Opt. Lett. 37, 4823-4825 (2012)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-37-23-4823


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