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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics


  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 2 — Mar. 4, 2013

Integrated optical- and acoustic-resolution photoacoustic microscopy based on an optical fiber bundle

Wenxin Xing, Lidai Wang, Konstantin Maslov, and Lihong V. Wang  »View Author Affiliations

Optics Letters, Vol. 38, Issue 1, pp. 52-54 (2013)

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Photoacoustic microscopy (PAM), whose spatial resolution and maximum imaging depth are both scalable, has made great progress in recent years. However, each PAM system currently achieves only one resolution with an associated maximum imaging depth. Here, we present an integrated optical-resolution (OR) and acoustic-resolution (AR) PAM system implemented by delivering light via an optical fiber bundle. A single fiber core is used to deliver light for OR illumination in order to achieve a small spot size and hence high lateral resolution, whereas all the fiber cores are used to deliver more energy for AR illumination. Most other components are shared by the OR and AR imaging. The lateral resolution can be seamlessly switched between 2.2 and 40 μm as the maximum imaging depth is switched between 1.3 and 3.0 mm. The system enables automatically coregistered higher-resolution OR and deeper AR photoacoustic imaging.

© 2012 Optical Society of America

OCIS Codes
(170.3880) Medical optics and biotechnology : Medical and biological imaging
(170.5120) Medical optics and biotechnology : Photoacoustic imaging

ToC Category:
Medical Optics and Biotechnology

Original Manuscript: August 30, 2012
Revised Manuscript: November 15, 2012
Manuscript Accepted: November 27, 2012
Published: December 20, 2012

Virtual Issues
Vol. 8, Iss. 2 Virtual Journal for Biomedical Optics

Wenxin Xing, Lidai Wang, Konstantin Maslov, and Lihong V. Wang, "Integrated optical- and acoustic-resolution photoacoustic microscopy based on an optical fiber bundle," Opt. Lett. 38, 52-54 (2013)

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