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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 7 — Aug. 1, 2013

Visible-light optical coherence tomography for retinal oximetry

Ji Yi, Qing Wei, Wenzhong Liu, Vadim Backman, and Hao F. Zhang  »View Author Affiliations


Optics Letters, Vol. 38, Issue 11, pp. 1796-1798 (2013)
http://dx.doi.org/10.1364/OL.38.001796


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Abstract

We applied a visible-light spectroscopic optical coherence tomography (vis-OCT) for in vivo retinal oximetry. To extract hemoglobin oxygen saturation (sO2) in individual retinal vessels, we established a comprehensive analytical model to describe optical absorption, optical scattering, and blood cell packing factor in the whole blood and fit the acquired vis-OCT signals from the bottom of each imaged vessel. We found that averaged sO2 values in arterial and venous bloods were 95% and 72%, respectively.

© 2013 Optical Society of America

OCIS Codes
(170.1470) Medical optics and biotechnology : Blood or tissue constituent monitoring
(170.4500) Medical optics and biotechnology : Optical coherence tomography

ToC Category:
Medical Optics and Biotechnology

History
Original Manuscript: March 5, 2013
Manuscript Accepted: April 19, 2013
Published: May 20, 2013

Virtual Issues
Vol. 8, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Ji Yi, Qing Wei, Wenzhong Liu, Vadim Backman, and Hao F. Zhang, "Visible-light optical coherence tomography for retinal oximetry," Opt. Lett. 38, 1796-1798 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-38-11-1796


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