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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 7 — Aug. 1, 2013

Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor

Seung Ah Lee, Xiaoze Ou, J. Eugene Lee, and Changhuei Yang  »View Author Affiliations


Optics Letters, Vol. 38, Issue 11, pp. 1817-1819 (2013)
http://dx.doi.org/10.1364/OL.38.001817


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Abstract

We demonstrate a silo-filter (SF) complementary metal-oxide semiconductor (CMOS) image sensor for a chip-scale fluorescence microscope. The extruded pixel design with metal walls between neighboring pixels guides fluorescence emission through the thick absorptive filter to the photodiode of a pixel. Our prototype device achieves 13 μm resolution over a wide field of view ( 4.8 mm × 4.4 mm ). We demonstrate bright-field and fluorescence longitudinal imaging of living cells in a compact, low-cost configuration.

© 2013 Optical Society of America

OCIS Codes
(110.0180) Imaging systems : Microscopy
(180.2520) Microscopy : Fluorescence microscopy

ToC Category:
Microscopy

History
Original Manuscript: March 13, 2013
Manuscript Accepted: April 8, 2013
Published: May 21, 2013

Virtual Issues
Vol. 8, Iss. 7 Virtual Journal for Biomedical Optics

Citation
Seung Ah Lee, Xiaoze Ou, J. Eugene Lee, and Changhuei Yang, "Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor," Opt. Lett. 38, 1817-1819 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-38-11-1817


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