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Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 8 — Sep. 4, 2013

X-ray luminescence optical tomography imaging: experimental studies

Changqing Li, Kun Di, Julien Bec, and Simon R. Cherry  »View Author Affiliations


Optics Letters, Vol. 38, Issue 13, pp. 2339-2341 (2013)
http://dx.doi.org/10.1364/OL.38.002339


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Abstract

We present a hybrid imaging modality, x-ray luminescence optical tomography (XLOT), in which collimated x-ray beams are used to excite phosphor-based contrast agents. Images are reconstructed from the optical signals, using the known x-ray beam location and spatial extent as priors. We demonstrate XLOT using phantom experiments with deep targets and show that the reconstructed signal varies by <12% when the depth changes from 4.2 to 7.7 mm. For simple source distributions, we find as few as two orthogonal projection measurements are sufficient for XLOT reconstruction.

© 2013 Optical Society of America

OCIS Codes
(110.7050) Imaging systems : Turbid media
(110.7440) Imaging systems : X-ray imaging
(110.6955) Imaging systems : Tomographic imaging

ToC Category:
Imaging Systems

History
Original Manuscript: April 26, 2013
Manuscript Accepted: May 16, 2013
Published: June 27, 2013

Virtual Issues
Vol. 8, Iss. 8 Virtual Journal for Biomedical Optics

Citation
Changqing Li, Kun Di, Julien Bec, and Simon R. Cherry, "X-ray luminescence optical tomography imaging: experimental studies," Opt. Lett. 38, 2339-2341 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-38-13-2339

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