OSA's Digital Library

Virtual Journal for Biomedical Optics

Virtual Journal for Biomedical Optics

| EXPLORING THE INTERFACE OF LIGHT AND BIOMEDICINE

  • Editors: Andrew Dunn and Anthony Durkin
  • Vol. 8, Iss. 10 — Nov. 8, 2013

Doubling the resolution of spatial-light-modulator-based differential interference contrast microscopy by structured illumination

Jianling Chen, Xiaohua Lv, and Shaoqun Zeng  »View Author Affiliations


Optics Letters, Vol. 38, Issue 17, pp. 3219-3222 (2013)
http://dx.doi.org/10.1364/OL.38.003219


View Full Text Article

Enhanced HTML    Acrobat PDF (323 KB)





Browse Journals / Lookup Meetings

Browse by Journal and Year


   


Lookup Conference Papers

Close Browse Journals / Lookup Meetings

Article Tools

Share
Citations

Abstract

Recently developed spatial light modulator (SLM)-based differential interference contrast (DIC) microscopy [Opt. Lett. 34, 2988 (2009)] reveals flexibility on the implementation of DIC imaging. However, its numerical aperture (spatial resolution) is limited to maintain sufficient interference contrast, because it requires two beams to interfere. We present a structured illumination (SI) SLM-based DIC microscopy to effectively improve the lateral resolution of the SLM-based DIC microscopy. The SI field is generated and controlled by an adjustable grating displayed on an SLM. The SI SLM-based DIC expands the bandwidth of the coherent transfer function of the SLM-based DIC imaging system, thus improving the spatial resolution. The reconstructed SI SLM-based DIC image exhibits lateral resolution of approximately 208 nm, doubling that of the common SLM-based DIC image (approximately 415 nm). SI SLM-based DIC microscopy has the potential for achieving high-resolution quantitative phase images.

© 2013 Optical Society of America

OCIS Codes
(100.6640) Image processing : Superresolution
(110.1650) Imaging systems : Coherence imaging
(180.3170) Microscopy : Interference microscopy

ToC Category:
Microscopy

History
Original Manuscript: July 5, 2013
Manuscript Accepted: July 22, 2013
Published: August 19, 2013

Virtual Issues
Vol. 8, Iss. 10 Virtual Journal for Biomedical Optics

Citation
Jianling Chen, Xiaohua Lv, and Shaoqun Zeng, "Doubling the resolution of spatial-light-modulator-based differential interference contrast microscopy by structured illumination," Opt. Lett. 38, 3219-3222 (2013)
http://www.opticsinfobase.org/vjbo/abstract.cfm?URI=ol-38-17-3219


Sort:  Author  |  Year  |  Journal  |  Reset  

References

  1. G. Nomarski, J. Phys. Radium 16, 9S (1955).
  2. D. Fu, S. Oh, W. Choi, T. Yamauchi, A. Dorn, Z. Yaqoob, R. R. Dasari, and M. S. Feld, Opt. Lett. 35, 2370 (2010). [CrossRef]
  3. M. R. Arnison, K. G. Larkin, C. Sheppard, N. I. Smith, and C. J. Cogswell, J. Microsc. 214, 7 (2004). [CrossRef]
  4. R. Danz, A. Vogelgsang, and R. K. A. Thner, Photonik 1, 42 (2004).
  5. X. Q. Cui, M. Lew, and C. H. Yang, Appl. Phys. Lett. 93, 911139 (2008).
  6. T. J. McIntyre, C. Maurer, S. Bernet, and M. Ritsch-Marte, Opt. Lett. 34, 2988 (2009). [CrossRef]
  7. S. Fürhapter, A. Jesacher, S. Bernet, and M. Ritsch-Marte, Opt. Express 13, 689 (2005). [CrossRef]
  8. A. Jesacher, U. F. S. Rhapter, S. Bernet, and M. Ritsch-Marte, Phys. Rev. Lett. 94, 233902 (2005). [CrossRef]
  9. C. Maurer, A. Jesacher, S. Bernet, and M. Ritsch-Marte, Opt. Express 16, 19821 (2008). [CrossRef]
  10. J. A. Davis and D. M. Cottrell, Opt. Lett. 19, 496 (1994). [CrossRef]
  11. M. Warber, M. Hasler, T. Haist, and W. Osten, Proc. SPIE 8086, 80861E (2011). [CrossRef]
  12. M. G. L. Gustafsson, J. Microsc. 198, 82 (2000). [CrossRef]
  13. M. G. L. Gustafsson, D. A. Agard, and J. W. Sedat, Proc. SPIE 3919, 141 (2000). [CrossRef]
  14. J. L. Chen, Y. Xu, X. H. Lv, X. M. Lai, and S. Q. Zeng, Opt. Express 21, 112 (2013). [CrossRef]
  15. C. J. Cogswell, N. I. Smith, K. G. Larkin, and P. Hariharan, Proc. SPIE 2984, 72 (1997). [CrossRef]
  16. T. J. McIntyre, C. Maurer, S. Fassl, S. Khan, S. Bernet, and M. Ritsch-Marte, Opt. Express 18, 14063 (2010). [CrossRef]
  17. T. A. Smith, L. M. Hirvonen, C. N. Lincoln, and X. Hao, J. Innov. Opt. Health Sci. 05, 1250025 (2012). [CrossRef]
  18. Y. A. Ushenko, J. Innov. Opt. Health Sci. 05, 1150001 (2012). [CrossRef]

Cited By

Alert me when this paper is cited

OSA is able to provide readers links to articles that cite this paper by participating in CrossRef's Cited-By Linking service. CrossRef includes content from more than 3000 publishers and societies. In addition to listing OSA journal articles that cite this paper, citing articles from other participating publishers will also be listed.

Figures

Fig. 1. Fig. 2. Fig. 3.
 

« Previous Article  |  Next Article »

OSA is a member of CrossRef.

CrossCheck Deposited